(Z)-Flunarizine

CAS: 693765-11-6

Ref. TR-F455205

Produktinformation

• Name: (Z)-Flunarizine
• Synonyme: Piperazine, 1-[bis(4-fluorophenyl)methyl]-4-[(2Z)-3-phenyl-2-propen-1-yl]-, Piperazine, 1-[bis(4-fluorophenyl)methyl]-4-[(2Z)-3-phenyl-2-propenyl]- (9CI), 1-[Bis(4-fluorophenyl)methyl]-4-[(2Z)-3-phenyl-2-propen-1-yl]piperazine, 1-[Bis(4-fluorophenyl)methyl]-4-[(2Z)-3-phenylprop-2-enyl]piperazine

Beschreibung

Impurity Flunarizine EP Impurity D
Applications (Z)-Flunarizine is Z-isomer of Flunarizine(F455200, Dihydrochloride), which is a calcium channel blocker. Flunarizine is a fluorinated derivative of Cinnarizine and a vasodilator (cerebral and peripheral). EP Impurity C
References Desmedt, L.K., et al.: Arzneim.-Forsch., 25, 1408 (1975), Godfraind, T., et al.: Eur. J. Pharmacol., 53, 273 (1979), Nihard, P., et al.: Angiology, 33, 37 (1982), Holmes, B., et al.: Drugs, 27, 6 (1984),

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 404.49
• Formel: C₂₆H₂₆F₂N₂
• Farbe/Form: Neat
• InChl: InChI=1S/C26H26F2N2/c27-24-12-8-22(9-13-24)26(23-10-14-25(28)15-11-23)30-19-17-29(18-20-30)16-4-7-21-5-2-1-3-6-21/h1-15,26H,16-20H2/b7-4-
• InChI Key: InChIKey=SMANXXCATUTDDT-DAXSKMNVSA-N
• SMILES: Fc1ccc(C(c2ccc(F)cc2)N2CCN(C/C=C\c3ccccc3)CC2)cc1