Fluasterone

CAS: 112859-71-9

Ref. TR-F500300

Produktinformation

• Name: Fluasterone
• Synonyme: (8R,9S,10R,13S,14S,16R)-16-fluoro-10,13-dimethyl-1,2,3,4,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-17-one, (16Alpha)-16-Fluoroandrost-5-En-17-One, (16α)-16-Fluoroandrost-5-en-17-one, (8R,9S,10R,13S,14S)-16-fluoro-10,13-dimethyl-1,2,3,4,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-17-one, 16alpha-Fluoro-5-androsten-17-one, 16α-Fluoro-5-androsten-17-one, Androst-5-en-17-one, 16-fluoro-, (16alpha)-, Androst-5-en-17-one, 16-fluoro-, (16α)-, Ccris 4216

Beschreibung

Applications A synthetic derivative of Dehydroepiandrosterone. The reduced androgenicity of Fluasterone may obviate toxicities associated with the androgenicity of the parent compound. Antitumor agent. Used in clinical trials for prostate cancer prevention.
References Bentley, P., et al.: Food Chem. Toxicol., 31, 857 (1993), Rao, K., et al.: Cancer Res., 59, 3084 (1999), Masuzaki, H., et al.: Science, 294, 2166 (2001), Osawa, E., et al.: Life Sci., 70, 2623 (2002),

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 290.42
• Formel: C₁₉H₂₇FO
• Farbe/Form: Neat
• InChl: InChI=1S/C19H27FO/c1-18-9-4-3-5-12(18)6-7-13-14(18)8-10-19(2)15(13)11-16(20)17(19)21/h6,13-16H,3-5,7-11H2,1-2H3/t13-,14+,15+,16-,18+,19+/m1/s1
• InChI Key: InChIKey=VHZXNQKVFDBFIK-NBBHSKLNSA-N
• SMILES: C[C@]12CC[C@H]3[C@@H](CC=C4CCCC[C@@]43C)[C@@H]1C[C@@H](F)C2=O