Fumaric Acid Monoethyl Ester

CAS: 2459-05-4

Ref. TR-F500385

Produktinformation

• Name: Fumaric Acid Monoethyl Ester
• Synonyme: (2E)-2-Butenedioic acid 1-ethyl ester, 2-Butenedioic acid (2E)-, monoethyl ester (9CI), 2-Butenedioic acid (E)-, monoethyl ester, Fumaric acid, ethyl ester (6CI,7CI), Fumaric acid, monoethyl ester (8CI), (E)-4-Ethoxy-4-oxo-2-butenoic acid, Ethyl hydrogen fumarate, Monoethyl fumarate, Monoethyl fumerate, Monoethyl trans-2-butenedioate, (2E)-4-ethoxy-4-oxobut-2-enoic acid, (2E)-4-ethoxy-4-oxobut-2-enoic acid - zinc (1:1), (E)-4-Ethoxy-4-oxobut-2-enoic acid, 2-Butenedioic acid (2E)-, 1-ethyl ester, 2-Butenedioic acid (2E)-, monoethyl ester, 2-Butenedioic acid (E)-, monoethyl ester, 4-Ethoxy-4-Oxobut-2-Enoate, Ethyl Fumarate, Fumaric acid, ethyl ester, Mono-Ethyl Fumarate, calcium dihydride - (2E)-4-ethoxy-4-oxobut-2-enoic acid (1:1), lithium (2E)-4-ethoxy-4-oxobut-2-enoate, sodium (2Z)-4-ethoxy-4-oxobut-2-enoate

Beschreibung

Impurity Quetiapine EP Impurity R
Applications Fumaric Acid Monoethyl Ester (Quetiapine EP Impurity R) is an anti-psoriatic fumaric acid ester. Fumaric Acid Monoethyl Ester inhibited thymidine-14C incorporation into DNA by cultured human lymphocytes. Fumaric Acid Monoethyl Ester has been shown to evoke transient increase in intracellular free calcium concentration and inhibit proliferation of human keratinocytes.
References Hagedorn, M. et al.: Arch. Dermatol. Res., 254, 67 (1975); Thio, H.B. et al.: Br. J. Dermatol., 131, 856 (1994); Rostami-Yazdi, M. Arch. Dermatol. Res., 302, 531 (2010);

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 144.13
• Formel: C₆H₈O₄
• Farbe/Form: Neat
• InChl: InChI=1S/C6H8O4/c1-2-10-6(9)4-3-5(7)8/h3-4H,2H2,1H3,(H,7,8)/b4-3+
• InChI Key: InChIKey=FXUKKQSINSXDFT-UHFFFAOYSA-N
• SMILES: CC(=O)Nc1ccc(-c2ccccc2)cn1