Fumaric Acid Monomethyl Ester-d5

CAS: 1616345-45-9

Ref. TR-F500393

Produktinformation

• Name: Fumaric Acid Monomethyl Ester-d5
• Synonyme: (2E)-2-Butenedioic Acid 1-Methyl Ester-d5, (E)-2-Butenedioic Acid Monomethyl Ester-d5, Fumaric Acid Methyl Ester-d5, Methyl Hydrogen Fumarate-d5, Monomethyl Fumarate-d5
• Marke: TRC
• Beschreibung: Applications Fumaric Acid Monomethyl Ester-d5 is the isotope labelled analog of Fumaric Acid Monomethyl Ester. Fumaric acid monomethyl ester is one of the most bioactive anti-psoriatic fumaric acid ester metabolite. Fumaric acid monomethyl ester is potent nicotinic acid receptor agonist. Fumaric acid monomethyl ester has also been shown to selectively stimulate of T helper 2 cytokine response. It is also the active metabolite of Dimethyl Fumarate (D464965), a compound that is used as a treatment for the relapsing forms of multiple sclerosis and psoriasis.References de Jong, R. et al.: Eur. J. Immunol., 26, 2067 (1996); Litjens, N.H.R. et al.: Br. J. Dermatol., 154, 211 (2006); Schimrigk, S., et al.: Eur. J. Neurol., 13, 604 (2006); Tang, H. et al.: Biochem. Biophys. Res. Comm., 375, 562 (2008)

Chemische Eigenschaften

• Molekulargewicht: 135.13
• Formel: C₅HD₅O₄
• Farbe/Form: Neat
• InChl: InChI=1S/C5H6O4/c1-9-5(8)3-2-4(6)7/h2-3H,1H3,(H,6,7)/b3-2+/i1D3,2D,3D
• InChI Key: InChIKey=NKHAVTQWNUWKEO-PWYLTMEHSA-N
• SMILES: [2H]/C(C(=O)O)=C(/[2H])C(=O)OC([2H])([2H])[2H]