N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-2,6-dimethyl-L-tyrosine

CAS: 206060-54-0

Ref. TR-F532440

Produktinformation

• Name: N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-2,6-dimethyl-L-tyrosine
• Synonyme: Fmoc-L-(2,6-di-Me)Tyr-OH
• Marke: TRC

Beschreibung

Applications N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-2,6-dimethyl-L-tyrosine can be used as reactant/reagent in cyclic tetrapeptide ("Cyclodal") and its mirror-image isomer are both high-affinity μ opioid receptor antagonists.
References Weltrowska, G., et al.: J Med Chem, 59, 9243 (2016);

Chemische Eigenschaften

• Molekulargewicht: 431.48
• Formel: C₂₆H₂₅NO₅
• Farbe/Form: Neat
• InChl: InChI=1S/C26H25NO5/c1-15-11-17(28)12-16(2)22(15)13-24(25(29)30)27-26(31)32-14-23-20-9-5-3-7-18(20)19-8-4-6-10-21(19)23/h3-12,23-24,28H,13-14H2,1-2H3,(H,27,31)(H,29,30)/t24-/m0/s1
• InChI Key: InChIKey=RHSSAHKTHNKPGU-DEOSSOPVSA-N
• SMILES: Cc1cc(O)cc(C)c1C[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O