8-Fluoro Erythromycin

CAS: 82664-20-8

Ref. TR-F591585

Produktinformation

• Name: 8-Fluoro Erythromycin
• Synonyme: Erythromycin, 8-fluoro- (9CI), Oxacyclotetradecane, erythromycin deriv., (8S)-8-Fluoroerythromycin A, 8-Fluoroerythromycin, 8-Fluoroerythromycin A, Antibiotic P 80206, Flurithromycin, P 0501A, P 80206, (3R,4S,5S,6R,7R,9S,11R,12R,13S,14R)-6-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-14-ethyl-9-fluoro-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-3,5,7,9,11,13-hexamethyloxacyclotetradecane-2,10-dione (non-preferred name), (8S)-8-Fluoroerythromycin, Cl-932, Erythromycin, 8-fluoro-, Flurithromycin [INN], Flurithromycine, Flurithromycine [French], Fluritromicina, Fluritromicina [Spanish], Fluritromycinum, Fluritromycinum [Latin], Oxacyclotetradecane, erythromycin deriv., P-0501A, Unii-56C9Dte69V

Beschreibung

Applications A fluorinated derivative of Erythromycin (E649950). A macrolide antibiotic.
References Labro, M. et al.: Macrolide Antibiot., 37 (2002); Lo Bue, A.M. et al.: J. Chemother., 13, 255 (2001); Fera, M.T. et al.: Int. J. Antimicrob. Agents, 17, 151 (2001);

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 751.92
• Formel: C₃₇H₆₆FNO₁₃
• Farbe/Form: Off-White
• InChl: InChI=1S/C37H66FNO13/c1-14-24-37(10,46)29(42)21(5)28(41)34(7,38)17-35(8,45)31(52-33-26(40)23(39(11)12)15-18(2)48-33)19(3)27(20(4)32(44)50-24)51-25-16-36(9,47-13)30(43)22(6)49-25/h18-27,29-31,33,40,42-43,45-46H,14-17H2,1-13H3/t18-,19+,20-,21+,22+,23+,24-,25+,26-,27+,29-,30+,31-,33+,34+,35-,36-,37-/m1/s1
• InChI Key: InChIKey=XOEUHCONYHZURQ-HNUBZJOYSA-N
• SMILES: CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@H](N(C)C)[C@H]2O)[C@](C)(O)C[C@](C)(F)C(=O)[C@H](C)[C@@H](O)[C@]1(C)O