Fluticasone 17β-Carboxylic Acid Propionate

CAS: 65429-42-7

Ref. TR-F599495

Produktinformation

• Name: Fluticasone 17β-Carboxylic Acid Propionate
• Synonyme: Androsta-1,4-diene-17-carboxylic acid, 6,9-difluoro-11-hydroxy-16-methyl-3-oxo-17-(1-oxopropoxy)-, (6alpha,11beta,16alpha,17alpha)-, 6alpha,9-difluoro-11beta-hydroxy-16alpha-methyl-3-oxo-17-(propanoyloxy)androsta-1,4-diene-17beta-carboxylic acid, Fluticasone Propionate Imp. A (EP), GR 36264X, Ph Eur Fluticasone Propionate Impurity A, unidentified impurity with RRT 1.23, disulphide dipropionate dithioketone (GR 247095X), hydroxyacid propionate (GR 36264X), dithio (GR 269949X), Fluticasone Propionate Impurity A, (6alpha,11beta,16alpha,17alpha)-6,9-Difluoro-11-hydroxy-16-methyl-3-oxo-17-(propionyloxy)androsta-1,4-diene-17-carboxylic acid, Androsta-1,4-Diene-17-Carboxylic Acid, 6,9-Difluoro-11-Hydroxy-16-Methyl-3-Oxo-17-(1-Oxopropoxy)-, (6Alpha,11Beta,16Alpha,17Alpha)-, (6Alpha,11Beta,16Alpha,17Alpha)-6,9-Difluoro-11-Hydroxy-16-Methyl-3-Oxo-17-(Propanoyloxy)Androsta-1,4-Diene-17-Carboxylic Acid

Beschreibung

Impurity Fluticasone Propionate EP Impurity A
Applications An impurity formed in the synthesis of Fluticasone propionate (F599500).
References Phillips, G., et al.: J. Med. Chem., 37, 3717 (1994),

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 452.49
• Formel: C₂₄H₃₀F₂O₆
• Farbe/Form: White
• InChl: InChI=1S/C24H30F2O6/c1-5-19(29)32-24(20(30)31)12(2)8-14-15-10-17(25)16-9-13(27)6-7-21(16,3)23(15,26)18(28)11-22(14,24)4/h6-7,9,12,14-15,17-18,28H,5,8,10-11H2,1-4H3,(H,30,31)/t12-,14+,15+,17+,18+,21+,22+,23+,24+/m1/s1
• InChI Key: InChIKey=DEDYNJVITFVPOG-CQRCZTONSA-N
• SMILES: CCC(=O)O[C@]1(C(=O)O)[C@H](C)C[C@H]2[C@@H]3C[C@H](F)C4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@@]21C