rac-Frovatriptan Acid

Ref. TR-F768510

Produktinformation

• Name: rac-Frovatriptan Acid
• Synonyme: 3-(Methylamino)-2,3,4,9-tetrahydro-1H-carbazole-6-carboxylic Acid

Beschreibung

Applications rac-Frovatriptan Acid is a metabolite of ent-Frovatriptan (F768505) which is a serotonin 5-HT1B/1D receptor agonist. It is a triptan drug for the treatment of migraine headaches. Frovatriptan causes vasoconstriction of arteries and veins that supply blood to the head.
References Parsons, A.A., et al.: J. Cardiovasc. Pharmacol., 30, 136 (1997), Siow, C.H., et al.: Cephalalgia, 24, 1045 (2004), Poolsup, N., et al.: J. Clin. Pharm. Ther., 30, 521 (2005),

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 244.29
• Formel: C₁₄H₁₆N₂O₂
• Farbe/Form: Neat
• InChl: InChI=1S/C14H16N2O2/c1-15-9-3-5-13-11(7-9)10-6-8(14(17)18)2-4-12(10)16-13/h2,4,6,9,15-16H,3,5,7H2,1H3,(H,17,18)
• InChI Key: InChIKey=VHMVURRYXKQJID-QMMMGPOBSA-N
• SMILES: O=CN[C@@H](Cc1cc(I)c(O)c(I)c1)C(=O)O