Fursultiamine

CAS: 804-30-8

Ref. TR-F865235

Produktinformation

• Name: Fursultiamine
• Synonyme: Formamide, N-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-N-[4-hydroxy-1-methyl-2-[[(tetrahydro-2-furanyl)methyl]dithio]-1-buten-1-yl]-, Formamide, N-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-N-[4-hydroxy-1-methyl-2-[(tetrahydrofurfuryl)dithio]-1-butenyl]- (6CI,8CI), Formamide, N-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-N-[4-hydroxy-1-methyl-2-[[(tetrahydro-2-furanyl)methyl]dithio]-1-butenyl]- (9CI), N-[(4-Amino-2-methyl-5-pyrimidinyl)methyl]-N-[4-hydroxy-1-methyl-2-[[(tetrahydro-2-furanyl)methyl]dithio]-1-buten-1-yl]formamide, Adventan, Alinamin F, Diteftin, Fursultiamin, Judolor, Linamin, N-[(4-Amino-2-methyl-5-pyrimidinyl)methyl]-N-[4-hydroxy-1-methyl-2-[(tetrahydrofurfuryl)dithio]-1-butenyl]formamide, Retar B1, TTFD, Tetrahydrofurfuryl thiamine disulfide, Thiamin tetrahydrofurfuryl disulfide
• Marke: TRC

Beschreibung

Applications Fursultiamine is an oral source of thiamine, used in comparative pharmacokinectic analysis of thiamine and it’s phosphorylated metabolites administered as multivitamin preparations, identification of drug candidate against prostate cancer from aspect of somatic cell reprogramming, therapeutic tool in number of human neurological diseases.
References Park, W., et al.: Clin. Ther., 38, 2277 (2016); Kosaka, T., et al.: Cancer Sci., 104, 1017 (2013); Lonsdale, D., et al.: Med. Sci. Monit., 10, 199 (2004)

Chemische Eigenschaften

• Molekulargewicht: 398.54
• Formel: C₁₇H₂₆N₄O₃S₂
• Farbe/Form: Neat
• InChl: InChI=1S/C17H26N4O3S2/c1-12(16(5-6-22)26-25-10-15-4-3-7-24-15)21(11-23)9-14-8-19-13(2)20-17(14)18/h8,11,15,22H,3-7,9-10H2,1-2H3,(H2,18,19,20)
• InChI Key: InChIKey=JTLXCMOFVBXEKD-FOWTUZBSSA-N
• SMILES: C/C(=C(/CCO)SSCC1CCCO1)N(C=O)Cc1cnc(C)[nH]c1=N