Gemfibrozil 1-O-β-D-(3,4,5-O-Triacetyl)glucuronide Methyl Ester

Ref. TR-G305775

Produktinformation

• Name: Gemfibrozil 1-O-β-D-(3,4,5-O-Triacetyl)glucuronide Methyl Ester
• Synonyme: Gemfibrozil (3,4,5-O-Triacetyl)glucuronide Methyl Ester,1-[5-(2,5-Dimethylphenoxy)-2,2-dimethylpentanoate] β-D-(3,4,5-O-Triacetyl)glucopyranuroic Acid Methyl Ester
• Marke: TRC
• Beschreibung: Applications Gemfibrozil 1-O-β-(3,4,5-O-Triacetyl)glucuronide Methyl Ester is an intermediate in the synthesis of Gemfibrozil 1-O-β-Glucuronide (G305760), the major metabolite of Gemfibrozil (G305750), a serum lipid regulating agent used as an antihyperlipoproteinemic.References Kissebach, A.H., et al.: Atherosclerosis, 24, 199 (1976); Lewis, J.E., et al.: Pract. Cardiol., 9, 99 (1983); Rubins, H.B., et al.: N. Engl. J. Med., 341, 410 (1999)

Chemische Eigenschaften

• Molekulargewicht: 566.59
• Formel: C₂₈H₃₈O₁₂
• Farbe/Form: Neat
• InChl: InChI=1S/C28H38O12/c1-15-10-11-16(2)20(14-15)35-13-9-12-28(6,7)27(33)40-26-24(38-19(5)31)22(37-18(4)30)21(36-17(3)29)23(39-26)25(32)34-8/h10-11,14,21-24,26H,9,12-13H2,1-8H3/t21-,22-,23-,24+,26-/m0/s1
• InChI Key: InChIKey=WVPFIVHYNMFASW-LSHRBJLDSA-N
• SMILES: COC(=O)[C@H]1O[C@@H](OC(=O)C(C)(C)CCCOc2cc(C)ccc2C)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O