d-Glaucine-d6

CAS: 475-81-0

Ref. TR-G406902

Produktinformation

• Name: d-Glaucine-d6
• Synonyme: (6aS)-5,6,6a,7-Tetrahydro-1,2,9,10-tetramethoxy-6-methyl-4H-dibenzo[de,g]quinoline-d6, (S)-5,6,6a,7-Tetrahydro-1,2,9,10-tetramethoxy-6-methyl-4H-dibenzo[de,g]quinoline-d6, 1,2,9,10-Tetramethoxy-6aα-aporphine-d6, Glaucine-d6, (+)-Glaucine-d6, (S)-Glaucine-d6, Boldine dimethyl ether-d6, Bromcholitin-d6, Glauvent-d6, N,O,O'-Trimethyllaurelliptine-d6, NSC 34396-d6, O,O-Dimethylboldine-d6, O,O-Dimethylisoboldine-d6
• Marke: TRC
• Beschreibung: Applications d-Glaucine-d6 is labelled d-Glaucine (G406900) which has bronchodilator and antiinflammatory effects, acting as a PDE4 inhibitor and calcium channel blocker, and is used medically as an antitussive in some countries.References Cortijo, J., et al.: Brit. J. Pharm., 127, 1641 (1999); Rühle, K., et al.: Brit. J. Clin. Pharm., 17, 521 (1984)

Chemische Eigenschaften

• Molekulargewicht: 361.46
• Formel: C₂₁H₁₉D₆NO₄
• Farbe/Form: Neat
• InChl: InChI=1S/C21H25NO4/c1-22-7-6-12-9-18(25-4)21(26-5)20-14-11-17(24-3)16(23-2)10-13(14)8-15(22)19(12)20/h9-11,15H,6-8H2,1-5H3/t15-/m0/s1/i2D3,4D3
• InChI Key: InChIKey=RUZIUYOSRDWYQF-LZROVGFOSA-N
• SMILES: [2H]C([2H])([2H])Oc1cc2c(cc1OC)-c1c(OC)c(OC([2H])([2H])[2H])cc3c1[C@H](C2)N(C)CC3