Glyoxylic Acid Hydrate-13C2

CAS: 918332-99-7

Ref. TR-G754997

Produktinformation

• Name: Glyoxylic Acid Hydrate-13C2
• Synonyme: 2,2-dihydroxyacetic acid

Beschreibung

Applications Glyoxylic Acid Hydrate-13C2 is the labelled hydrated analog of Glyoxylic Acid (G754995) which is used as a reagent in the synthesis of N-{[6-chloro-4-(2,6-dimethoxyphenyl)quinazolin-2-yl]carbonyl}-L-leucine, a novel nonpeptide chemotype selective for neurotensin receptor 2. Also used as a reagent in the synthesis of elemonic acid derivatives as Pin1 inhibitors. Glyoxylic Acid-13C2 was used in the synthesis of carbon labelled 6-N-carboxymethyllysine (CML) which is the most used marker for advanced glycation endproducts in food analysis.
References Thomas, J.B., et al.: Bioorg. Med. Chem. Lett., 25, 292 (2015); Li, X., et al.: Bioorg. Med. Chem. Lett., 24, 5612 (2014); Delatour, T., et al.: Amino Acids, 30, 25 (2006);

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 94.036
• Formel: C₂H₄O₄
• Farbe/Form: Neat
• InChl: InChI=1S/C2H4O4/c3-1(4)2(5)6/h1,3-4H,(H,5,6)/i1+1,2+1
• InChI Key: InChIKey=GOCCREQJUBABAL-ZDOIIHCHSA-N
• SMILES: O=[13C](O)[13CH](O)O