GS 39783

CAS: 39069-52-8

Ref. TR-G797150

Produktinformation

• Name: GS 39783
• Synonyme: 4-N,6-N-dicyclopentyl-2-methylsulfanyl-5-nitropyrimidine-4,6-diamine, 4,6-Pyrimidinediamine, N,N′-dicyclopentyl-2-(methylthio)-5-nitro-, 4,6-Pyrimidinediamine, N⁴,N⁶-dicyclopentyl-2-(methylthio)-5-nitro-, 4,6-Pyrimidinediamine, N~4~,N~6~-dicyclopentyl-2-(methylthio)-5-nitro-, Gs 39783, N,N'-dicyclopentyl-2-methylsulfanyl-5-nitro-pyrimidine-4,6-diamine, N⁴,N⁶-Dicyclopentyl-2-(methylthio)-5-nitro-4,6-pyrimidinediamine

Beschreibung

Applications GS 39783 is an allosteric positive modulator of GABAB receptors. GS 39783 attenuates acute cocaine-induced hyperlocomotion and blocks cocaine-induced Fos induction in the striatal complex.
References Paterson, N. et al.: J. Pharmacol. Exp. Ther., 326, 306 (2008); Mombereau, C. et al.: J. Pharmacol. Exp. Ther., 321, 172 (2007); Lhuillier, L. et al.: Neuropsychopharmacol., 32, 388 (2007); Slattery, D. et al.: Neuropharmacol., 30, 2065 (2005)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 337.44
• Formel: C₁₅H₂₃N₅O₂S
• Farbe/Form: Neat
• InChl: InChI=1S/C15H23N5O2S/c1-23-15-18-13(16-10-6-2-3-7-10)12(20(21)22)14(19-15)17-11-8-4-5-9-11/h10-11H,2-9H2,1H3,(H2,16,17,18,19)