Hydroxymethyl Emtricitabine

Ref. TR-H258740

Produktinformation

• Name: Hydroxymethyl Emtricitabine
• Synonyme: 5-fluoro-4-(hydroxymethylamino)-1-[(2S,5R)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2-one

Beschreibung

Applications Hydroxymethyl Emtricitabine is an impurity of Emtricitabine(E525000) which is a reverse transcriptase inhibitor. It is an effective antiviral agent against HIV, HBV, and other viruses replicating in a similar manner. A nucleoside analog structurally related to Lamivudine (L172500).
References FASEB J., 13, 1511 (1999), Molina, J.-M., et al.: J. InfecSchinazi, R.F., et al.: Antimicrob. Ag. Chemother., 36, 2423 (1992), Shockeor, J.P., et al.: Xenobioica, 26, 189 (1996), Feng, J.Y., et al.: . Dis., 182, 599 (2000)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 277.273
• Formel: C₉H₁₂FN₃O₄S
• Farbe/Form: Neat
• InChl: InChI=1S/C9H12FN3O4S/c10-5-1-13(6-3-18-7(2-14)17-6)9(16)12-8(5)11-4-15/h1,6-7,14-15H,2-4H2,(H,11,12,16)/t6-,7+/m1/s1
• InChI Key: InChIKey=BWHXGDDIHAZYQK-RQJHMYQMSA-N
• SMILES: O=c1nc(NCO)c(F)cn1[C@H]1CS[C@@H](CO)O1