Honokiol

CAS: 35354-74-6

Ref. TR-H669560

Produktinformation

• Name: Honokiol
• Synonyme: 3',5-Di-2-propen-1-yl-[1,1'-biphenyl]-2,4'-diol, [1,1'-Biphenyl]-2,4'-diol, 3',5-di-2-propenyl- (9CI), 3',5-Diallyl-2,4'-biphenyldiol, NSC 293100, 2-Allyl-4-(5-allyl-2-hydroxyphenyl)phenol, 2-[4-Hydroxy-3-(2-propenyl)phenyl]-4-(2-propenyl)phenol, 3',5-Di(Prop-2-En-1-Yl)Biphenyl-2,4'-Diol, 3,5'-Diallyl-4,2'-dihydroxybiphenyl, 3′,5-Di-2-propen-1-yl[1,1′-biphenyl]-2,4′-diol, 3′,5-Diallyl-2,4′-biphenyldiol, Nsc 293100, [1,1′-Biphenyl]-2,4′-diol, 3′,5-di-2-propen-1-yl-, [1,1′-Biphenyl]-2,4′-diol, 3′,5-di-2-propenyl-

Beschreibung

Applications Honokiol is a small-molecule polyphenol isolated from the genus Magnolia. Recent studies show that Honokiol displays antiangiogenic, antiinflammatory, and antitumor properties in preclinical models, without appreciable toxicity. Honokiol has been shown to inhibit the bone metastatic growth of human prostate cancer cells.
References Fried, L.E. et al.: Antioxid. Redox Signal,. 11, 1139 (2009); Chen, X.R. et al.: Int. J. Oral Sci., 3, 34 (2011); Shigemura, K. et al.: Cancer, 109, 1279 (2007); Bai, X. et al.: J. Biol. Chem., 278, 35501 (2003);

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 266.33
• Formel: C₁₈H₁₈O₂
• Farbe/Form: Neat
• InChl: InChI=1S/C18H18O2/c1-3-5-13-7-9-18(20)16(11-13)14-8-10-17(19)15(12-14)6-4-2/h3-4,7-12,19-20H,1-2,5-6H2
• InChI Key: InChIKey=FVYXIJYOAGAUQK-UHFFFAOYSA-N
• SMILES: C=CCc1ccc(O)c(-c2ccc(O)c(CC=C)c2)c1