4’-Hydroxy Dutasteride

Ref. TR-H825530

Produktinformation

• Name: 4’-Hydroxy Dutasteride

Beschreibung

Applications 4’-Hydroxy Dutasteride is an impurity of Dutasteride (D735000), a dual inhibitor of 5α-reductase isoenzymes type 1 and 2; structurally related to Finasteride (F342000). Dutasteride is used in the treatment of benign prostatic hyperplasia.
References Bakshi, R.K., et al.: J. Med. Chem., 38, 3189 (1995), Gisleskog, P.O., et al.: Brit. J. Clin. Pharmacol., 47, 53 (1999), Djavan, B., et al.: Expert Opin. Pharmacother., 6, 311 (2005)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 544.53
• Formel: C₂₇H₃₀F₆N₂O₃
• Farbe/Form: Neat
• InChl: InChI=1S/C27H30F6N2O3/c1-24-9-7-15-13(3-6-21-25(15,2)10-8-22(37)35-21)14(24)4-5-16(24)23(38)34-19-11-18(27(31,32)33)20(36)12-17(19)26(28,29)30/h8,10-16,21,36H,3-7,9H2,1-2H3,(H,34,38)(H,35,37)/t13-,14-,15-,16+,21+,24-,25+/m0/s1
• InChI Key: InChIKey=WPHIZNQKPSLXES-RMEAINHRSA-N
• SMILES: C[C@]12CC[C@H]3[C@@H](CC[C@H]4NC(=O)C=C[C@]34C)[C@@H]1CC[C@@H]2C(=O)Nc1cc(C(F)(F)F)c(O)cc1C(F)(F)F