Des-(2-propyl-1,3-dioxolane)-2-hydroxy Budesonide

Ref. TR-H825825

Produktinformation

• Name: Des-(2-propyl-1,3-dioxolane)-2-hydroxy Budesonide
• Synonyme: 16,17-Dehydro-21-hydroxy-prednisolone

Beschreibung

Applications (8S,9S,10R,13S,14S)-17-(2,2-Dihydroxyacetyl)-11-hydroxy-10,13-dimethyl-6,7,8,9,10,11,12,13,14,15-decahydro-3H-cyclopenta[a]phenanthren-3-one is an impurity of budesonide which is a non-halogenated glucocorticoid related to triamcinolone hexacetonide. Used as an antiinflammatory agent.
References Ryrfeldt., A., et a.: J. Steroid Biochem., 10, 317 (1979), Roth, G., et al.: J. Pharm. Sci., 69, 766 (1980), Clissold, S.P., et al.: Drugs, 28, 485 (1984),

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 358.43
• Formel: C₂₁H₂₆O₅
• Farbe/Form: Neat
• InChl: InChI=1S/C21H26O5/c1-20-8-7-12(22)9-11(20)3-4-13-14-5-6-15(18(24)19(25)26)21(14,2)10-16(23)17(13)20/h6-9,13-14,16-17,19,23,25-26H,3-5,10H2,1-2H3/t13-,14-,16?,17+,20-,21-/m0/s1
• InChI Key: InChIKey=ZXKRFVYEBAKPSC-QJDVUWIWSA-N
• SMILES: C[C@]12CC(O)[C@@H]3[C@H](CCC4=CC(=O)C=C[C@@]43C)[C@@H]1CC=C2C(=O)C(O)O