rac trans-4-Hydroxy Glyburide

CAS: 23155-00-2

Ref. TR-H942625

Produktinformation

• Name: rac trans-4-Hydroxy Glyburide
• Synonyme: 5-chloro-N-[2-[4-[(4-hydroxycyclohexyl)carbamoylsulfamoyl]phenyl]ethyl]-2-methoxybenzamide, 4-trans-Hydroxycyclohexyl glyburide, 4-trans-Hydroxyglibenclamide, 5-Chloro-N-[2-[4-[[[[(trans-4-hydroxycyclohexyl)amino]carbonyl]amino]sulfonyl]phenyl]ethyl]-2-methoxybenzamide, Benzamide,5-chloro-N-[2-[4-[[[[(4-hydroxycyclohexyl)amino]carbonyl]amino]sulfonyl]phenyl]ethyl]-2-methoxy-,trans-, N-[4-[b-(2-Methoxy-5-chlorobenzamido)ethyl]benzenesulfonyl]-N'-(trans-4-hydroxycyclohexyl)urea, Urea, 1-[[p-[2-(5-chloro-o-anisamido)ethyl]phenyl]sulfonyl]-3-(4-hydroxycyclohexyl)-, trans-, Urea,1-[[p-[2-(5-chloro-o-anisamido)ethyl]phenyl]sulfonyl]-3-(4-hydroxycyclohexyl)-,trans- (8CI), trans-4-Hydroxyglyburide, trans-N-4-[2-(5-Chloro-2-methoxybenzamido)ethyl]phenylsulfonyl-N'-(4-hydroxycyclohexyl)urea, Benzamide, 5-chloro-N-[2-[4-[[[[(trans-4-hydroxycyclohexyl)amino]carbonyl]amino]sulfonyl]phenyl]ethyl]-2-methoxy-

Beschreibung

Stability Hygroscopic and Moisture Sensitive
Applications rac trans-4-Hydroxy Glyburide is a metabolite of Glyburide which is used as an antidiabetic.
References Heptner, W., et al.: Pharmaceut. Res., 5, 215 (1984), Rydberg, T., et al.: Br. J. Clin. Pharm., 43, 373 (1997),

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 510.00
• Formel: C₂₃H₂₈ClN₃O₆S
• Farbe/Form: Neat
• InChl: InChI=1S/C23H28ClN3O6S/c1-33-21-11-4-16(24)14-20(21)22(29)25-13-12-15-2-9-19(10-3-15)34(31,32)27-23(30)26-17-5-7-18(28)8-6-17/h2-4,9-11,14,17-18,28H,5-8,12-13H2,1H3,(H,25,29)(H2,26,27,30)/t17-,18-
• InChI Key: InChIKey=IUWSGCQEWOOQDN-IYARVYRRSA-N
• SMILES: COc1ccc(Cl)cc1C(=O)NCCc1ccc(S(=O)(=O)NC(=O)N[C@H]2CC[C@H](O)CC2)cc1