7Alpha-Hydroxyfrullanolide

CAS: 105578-87-8

Ref. TR-H942700

Produktinformation

• Name: 7Alpha-Hydroxyfrullanolide
• Synonyme: 3-methylenenaphtho[1,2-b]furan-2(3H)-one, 7a-Hydroxy-4,11(13)-eudesmadien-12,6-olide, (3aR,5aR,9bS)-3a,4,5,5a,6,7,8,9b-Octahydro-3a-hydroxy-5a,9-dimethyl-3-methylene-naphtho[1,2-b]furan-2(3H)-one

Beschreibung

Applications 7α-Hydroxyfrullanolide is a natural product extracted from the aerial parts of Sphaeranthus indicus. 7α-Hydroxyfrullanolide has cytotoxic and antimalarial effects. It can also inhibit migratory, proliferative activity and pro-inflammatory cytokine production in keratinocytes and immune cells.
References Sangsopha, Watchara, et al.: Phytochemistry Letters, 17, 278-281 (2016); Fonseca, Lyle C., et al.: Euro. J. of Pharmaco., 644(1-3), 220-229 (2010); Chakrabarti, Debarshi, et al.: Pharmaco. & Pharm., 3(2), 178-194 (2012)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 248.32
• Formel: C₁₅H₂₀O₃
• Farbe/Form: Light Yellow To Beige
• InChl: InChI=1S/C15H20O3/c1-9-5-4-6-14(3)7-8-15(17)10(2)13(16)18-12(15)11(9)14/h12,17H,2,4-8H2,1,3H3/t12-,14+,15+/m0/s1
• InChI Key: InChIKey=XMPDAVDYIOMTLX-NWANDNLSSA-N
• SMILES: C=C1C(=O)O[C@H]2C3=C(C)CCC[C@]3(C)CC[C@@]12O