(2S,4R)-4-Hydroxy-2-(hydroxymethyl)-1-pyrrolidinecarboxylic Acid tert-Butyl Ester

CAS: 61478-26-0

Ref. TR-H942835

Produktinformation

• Name: (2S,4R)-4-Hydroxy-2-(hydroxymethyl)-1-pyrrolidinecarboxylic Acid tert-Butyl Ester
• Synonyme: (2S,4R)-tert-Butyl 4-Hydroxy-2-(hydroxymethyl)pyrrolidine-1-carboxylate, N-Boc-trans-4-hydroxy-L-prolinol, tert-Butyl (2S,4R)-4-Hydroxy-2-(hydroxymethyl)pyrrolidine-1-carboxylate, tert-Butyl (2S,4R)-4-Hydroxy-2-hydroxymethylpyrrolidine-1-carboxylate, (-)-N-Boc-L-4-Hydroxyprolinol, (2S,4R)-tert-Butyl 4-hydroxy-2-(hydroxymethyl)pyrrolidine-1-carboxylate, 1,1-Dimethylethyl (2S,4R)-4-hydroxy-2-(hydroxymethyl)-1-pyrrolidinecarboxylate, 1-Pyrrolidinecarboxylic acid, 4-hydroxy-2-(hydroxymethyl)-, 1,1-dimethylethyl ester, (2S,4R)-, 1-Pyrrolidinecarboxylic acid, 4-hydroxy-2-(hydroxymethyl)-, 1,1-dimethylethyl ester, (2S-trans)-, Boc-Hyp-Ol, Boc-Trans-4-hydroxy-L-prolinol, N-Boc-trans-4-hydroxy-<span class="text-smallcaps">L</span>-prolinol, tert-Butyl (2S,4R)-4-hydroxy-2-hydroxymethylpyrrolidine-1-carboxylate, tert-butyl (2S,4R)-4-hydroxy-2-(hydroxymethyl)pyrrolidine-1-carboxylate

Beschreibung

Applications A useful reactant used in the preparation of 4-purinylpyrrolidine nucleosides, kinase inhibitors and antibacterial agents.
References Abraham, S. et al.: Bioorg. Med. Chem. Lett., 21, 5296 (2011); Huang, X. et al.: Bioorg. Med. Chem. Lett., 19, 4130 (2009); Peterson, M. & Vince, R.: J. Med. Chem., 34, 2787 (1991)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 217.26
• Formel: C₁₀H₁₉NO₄
• Farbe/Form: Neat
• InChl: InChI=1S/C10H19NO4/c1-10(2,3)15-9(14)11-5-8(13)4-7(11)6-12/h7-8,12-13H,4-6H2,1-3H3/t7-,8+/m1/s1
• InChI Key: InChIKey=UFJNFQNQLMGUTQ-SFYZADRCSA-N
• SMILES: CC(C)(C)OC(=O)N1C[C@@H](O)C[C@@H]1CO