2-Hydroxyisobutyric Acid

CAS: 594-61-6

Ref. TR-H942985

Produktinformation

• Name: 2-Hydroxyisobutyric Acid
• Synonyme: a-Hydroxyisobutyric Acid, 2-Methyllactic Acid, 2-Hydroxy-2-methylpropanoic Acid, 2,2-Dimethylglycolic Acid, 2-Hydroxy-2-methylpropionic Acid, Acetonic Acid, Alpha-hydroxyisobutanoic Acid, Hydroxydimethylacetic Acid, NSC 402158, NSC 4505, a-HIB, a-Hydroxy-a-methylpropanoic Acid, a-Hydroxyisobutanoic Acid, a-Hydroxyisobutyric Acid, 2,2-Dimethylglycolic acid, 2-Hydroxy-2-Methylpropanoate, 2-Hydroxy-2-methylpropanoic acid, 2-Hydroxy-2-methylpropionic acid, 2-Hydroxy-2-methylpropionsaure, 2-Hydroxyisobutanoic acid, 2-Methyllactic acid, 3-Hydroxy-2-Methylpropanoic Acid, Acetonic acid, Acide 2-hydroxy-2-methylpropionique, Acido 2-Hidroxi-2-Metilpropionico, Alpha-hydroxyisobutanoic acid, Hydroxydimethylacetic acid, Isobutyric acid, α-hydroxy-, Lactic acid, 2-methyl-, Nsc 402158, Nsc 4505, Propanoic acid, 2-hydroxy-2-methyl-, Propionic Acid, 2-Hydroxy-2-Methyl-, α-HIB, α-Hydroxy-α-methylpropanoic acid, α-Hydroxyisobutanoic acid, α-Hydroxyisobutyric acid

Beschreibung

Applications 2-Hydroxyisobutyric Acid is used as a reagent in the preparation of fully functionalized tetronic acids. Also used in the synthesis of bioisosteres of trimethadione, N-derivative-1,2,3-oxathiazolidine-4-one-2,2-dioxides from α-hydroxyamides which display anticonvulsant activity.
References Prousis, K., et al.: Tetrahedron, 71, 8637 (2015); Pastore, V., et al.: Bioorgan. Med. Chem., 21, 841 (2013);

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 104.1
• Formel: C₄H₈O₃
• Farbe/Form: White To Off-White
• InChl: InChI=1S/C4H8O3/c1-4(2,7)3(5)6/h7H,1-2H3,(H,5,6)
• InChI Key: InChIKey=BWLBGMIXKSTLSX-UHFFFAOYSA-N
• SMILES: CC(C)(O)C(=O)O