2-Hydroxy-5-methoxybenzimidazole

CAS: 2080-75-3

Ref. TR-H946100

Produktinformation

• Name: 2-Hydroxy-5-methoxybenzimidazole
• Synonyme: 5-Methoxy-1,3-dihydrobenzimidazol-2-one, 1,3-Dihydro-5-methoxy-2H-benzimidazole-2-one~2-Hydroxy-5-methoxybenzimidazole, 5-Methoxy-2(3H)-benzimidazolone, 5-methoxy-1,3-dihydro-2H-benzimidazol-2-one

Beschreibung

Applications Benzimidazole derivative. An intermediate for a novel class of 2-{3-oxospiro[isobenzofuran-1(3H),4'-piperidin]-1'-yl}benzimidazole NPY Y5 receptor antagonist. An impurity of Esomeprazole, which is a gastric proton-pump inhibitor.
References Tatemoto, K., et al.: Nature, 285, 417 (1980), Norman, M., et al.: J. Med. Chem., 43, 4288 (2000), Shibata, Y., et al.: Drug Metab. Dispos., 28, 1518 (2000), Gillman, K., et al.: Bioorg. Med. Chem., 14, 5517 (2006),

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 164.16
• Formel: C₈H₈N₂O₂
• Farbe/Form: Beige
• InChl: InChI=1S/C8H8N2O2/c1-12-5-2-3-6-7(4-5)10-8(11)9-6/h2-4H,1H3,(H2,9,10,11)
• InChI Key: InChIKey=AUPLVAKFTYFHTA-UHFFFAOYSA-N
• SMILES: COc1ccc2nc(O)[nH]c2c1