5-Hydroxy-1-methyl-4-nitroimidazole Sodium Salt (>90%)

CAS: 35681-68-6

Ref. TR-H947755

Produktinformation

• Name: 5-Hydroxy-1-methyl-4-nitroimidazole Sodium Salt (>90%)
• Synonyme: 1-Methyl-4-nitro-1H-imidazol-5-ol Sodium Salt, Azathioprine BP Impurity E, 1H-Imidazol-5-ol, 1-methyl-4-nitro-, sodium salt (1:1), 1H-Imidazol-5-ol, 1-methyl-4-nitro-, sodium salt

Beschreibung

Impurity Azathioprine BP Impurity E
Stability Light Sensitive
Applications 5-Hydroxy-1-methyl-4-nitroimidazole Sodium Salt is a degradation product of Azathioprine (A803350); an immunosuppressive antimetabolite that is also active as a disease modifying antirheumatic drug (DMARD).
References Mitrou, P.S., et al.: Arzneim.-Forsch., 29, 483, 662 (1979); Ding, T.L., et al.: Drug. Metab. Dispos., 7, 373 (1979); Chan, G.L.C., et al.: Pharmacotherapy, 7, 165 (1987); Sandborn, W.J., et al.: Scand. J. Gastroenterol., 33, Suppl. 225, 92 (1998)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 165.08
• Formel: C₄H₄N₃NaO₃
• Reinheit: >90%
• Farbe/Form: Light Yellow To Yellow
• SMILES: Cn1cnc([N+](=O)[O-])c1O[Na]