5-Hydroxy Omeprazole (~5% Triethylamine as stabilizer)

CAS: 92340-57-3

Ref. TR-H948110

Produktinformation

• Name: 5-Hydroxy Omeprazole (~5% Triethylamine as stabilizer)
• Synonyme: 4-Methoxy-6-[[(5-methoxy-1H-benzimidazol-2-yl)sulfinyl]methyl]-5-methyl-3-pyridinemethanol, 5-Methoxy-2-[[(4-methoxy-3-methyl-5-hydroxymethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole, Hydroxyomeprazole, (4-methoxy-6-{[(6-methoxy-1H-benzimidazol-2-yl)sulfinyl]methyl}-5-methylpyridin-3-yl)methanol, 3-Pyridinemethanol, 4-methoxy-6-[[(5-methoxy-1H-benzimidazol-2-yl)sulfinyl]methyl]-5-methyl-, 3-Pyridinemethanol, 4-methoxy-6-[[(6-methoxy-1H-benzimidazol-2-yl)sulfinyl]methyl]-5-methyl-, 4-Methoxy-6-[[(6-methoxy-1H-benzimidazol-2-yl)sulfinyl]methyl]-5-methyl-3-pyridinemethanol, [4-Methoxy-6-[(6-methoxy-1H-benzimidazol-2-yl)sulfinylmethyl]-5-methylpyridin-3-yl]methanol, 5-Hydroxyomeprazole

Beschreibung

Stability Hygroscopic, Temperature Sensitive
Applications 5-Hydroxy Omeprazole is the main metabolite of Omeprazole (O635000), which binds covalently to proton pump. It inhibits gastric secretion. Used as an anttiulcerative.
References Muller, P., et al.: Arzneimittel-Forsch., 33, 1685 (1983); Wallmark, B., et al.: Biochim. Biophys. Acta., 778, 549 (1984); Morii, M., et al.: J. Biol. chem., 268, 21553 (1993); Ritter, M., et al.: Br. J. Pharmacol., 124, 627 (1998)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 361.42
• Formel: C₁₇H₁₉N₃O₄S
• Farbe/Form: Neat
• InChl: InChI=1S/C17H19N3O4S/c1-10-15(18-7-11(8-21)16(10)24-3)9-25(22)17-19-13-5-4-12(23-2)6-14(13)20-17/h4-7,21H,8-9H2,1-3H3,(H,19,20)
• InChI Key: InChIKey=CMZHQFXXAAIBKE-UHFFFAOYSA-N
• SMILES: COc1ccc2[nH]c(S(=O)Cc3ncc(CO)c(OC)c3C)nc2c1