10Alpha-Hydroxy Naloxone

CAS: 2139253-68-0

Ref. TR-H948660

Produktinformation

• Name: 10Alpha-Hydroxy Naloxone
• Synonyme: 10a-Hydroxy Naloxone,(5a)-4,5-Epoxy-3,10a,14-trihydroxy-17-(2-propenyl)morphinan-6-one

Beschreibung

Impurity Naloxone EP Impurity C
Applications 10α-Hydroxy Naloxone is a hydroxylated analog of the opioid antagonist Naloxone (N285000(P)), which is a specific opioid antagonist; narcotic antagonist.
References Jasinski, D.R., et al.: J. Pharmacol. Exp. Ther., 157, 420 (1967), McNicholas, L.F., et al.: Drugs, 27, 81 (1984), Hasson, M.M.A., et al.: Anal. Profiles Drug Subs., 14, 453 (1985), Stowe, C., et al.: Ann. Pharmacother., 27, 447 (1993)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 343.37
• Formel: C₁₉H₂₁NO₅
• Farbe/Form: Neat
• InChl: InChI=1S/C19H21NO5/c1-2-8-20-9-7-18-13-10-3-4-11(21)15(13)25-17(18)12(22)5-6-19(18,24)16(20)14(10)23/h2-4,14,16-17,21,23-24H,1,5-9H2/t14-,16+,17-,18-,19+/m0/s1
• InChI Key: InChIKey=INQPEYLRYLSPCY-YCVVXREPSA-N
• SMILES: C=CCN1CC[C@]23c4c5ccc(O)c4O[C@H]2C(=O)CC[C@@]3(O)[C@H]1[C@H]5O