(R)-4-(4-Hydroxyphenyl)-2,5-oxazolidinedione

CAS: 26889-96-3

Ref. TR-H951315

Produktinformation

• Name: (R)-4-(4-Hydroxyphenyl)-2,5-oxazolidinedione
• Synonyme: (-)-4-(p-Hydroxyphenyl)-2,5-oxazolidinedione, D-(-)-p-Hydroxy-N-carboxyphenylglycyl Anhydride, D-4-Hydroxyphenylglycine N-carboxyanhydride
• CAS: 26889-96-3

Beschreibung

Applications (R)-4-(4-Hydroxyphenyl)-2,5-oxazolidinedione is a cyclic anhydride and intermediate in the synthesis of 3-(4-Hydroxyphenyl)-2(1H)-pyrazinone (H951260), which is a potential impuritiy of the penicillins, ampicillin and amoxicillin, which have not been reported previously. 3-(4-Hydroxyphenyl)-2(1H)-pyrazinone impurity may be formed during the semi-synthetic preparation of these antibiotics or upon their degradation.
References Munro, A., et al.: J. Pharm. Sci., 67, 1197 (1978); Lebelle, M., et al.: J. Pharm. Pharmacol., 31, 441 (1979)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 193.16
• Formel: C₉H₇NO₄
• Farbe/Form: Light Yellow Solid
• InChl: InChI=1S/C9H7NO4/c11-6-3-1-5(2-4-6)7-8(12)14-9(13)10-7/h1-4,7,11H,(H,10,13)/t7-/m1/s1
• InChI Key: InChIKey=CBVYRRXBGXLNRT-SSDOTTSWSA-N
• SMILES: O=C1N[C@H](c2ccc(O)cc2)C(=O)O1