Boc-trans-Hydroxy-L-proline

CAS: 13726-69-7

Ref. TR-H952495

Produktinformation

• Name: Boc-trans-Hydroxy-L-proline
• Synonyme: (2S-trans)-4-Hydroxy-1,2-Pyrrolidinedicarboxylic Acid 1-(1,1-Dimethylethyl) Ester, L-4-Hydroxy-1,2-pyrrolidinedicarboxylic Acid 1-tert-Butyl Ester, (2S,4R)-1-(tert-Butoxycarbonyl)-4-hydroxypyrrolidine-2-carboxylic Acid, (2S,4R)-4-Hydroxy-1-(tert-butoxycarbonyl)pyrrolidine-2-carboxylic Acid, (2S,4R)-4-Hydroxy-1-[(2-methylpropan-2-yl)oxycarbonyl]pyrrolidine-2-carboxylic Acid, (2S,4R)-4-Hydroxypyrrolidine-1,2-dicarboxylic Acid 1-tert-Butyl Ester, (4R)-1-(tert-Butoxycarbonyl)-4-hydroxy-L-proline, 1-(tert-Butoxycarbonyl)-(2S,4R)-4-hydroxypyrrolidine-2-carboxylic Acid, Boc-L-trans-gamma-hydroxyproline, N-(tert-Butoxycarbonyl)-4-hydroxy-L-proline, N-(tert-Butoxycarbonyl)hydroxy-L-proline, N-(tert-Butoxycarbonyl)hydroxyproline, N-(tert-Butyloxycarbonyl)-4-hydroxyproline, N-Boc-trans-4-hydroxy-L-proline, N-tert-Butoxycarbonyl-(4R)-4-hydroxy-L-proline, NSC 343720, trans-1-(tert-Butoxycarbonyl)-4-hydroxy-L-proline, (2S,4R)-1-(tert-Butoxycarbonyl)-4-hydroxypyrrolidine-2-carboxylic Acid, (2S,4R)-1-(tert-butoxycarbonyl)-4-hydroxypyrrolidine-2-carboxylic acid, (2S,4R)-1-(tertbutoxycarbonyl)-4-hydroxypyrrolidine carboxylic acid, (2S,4R)-1-Boc-4-Hydroxy-Proline, (2S,4R)-4-Hydroxy-1-(tert-butoxycarbonyl)pyrrolidine-2-carboxylic acid, (2S,4R)-4-Hydroxy-1-[(2-methylpropan-2-yl)oxycarbonyl]pyrrolidine-2-carboxylic acid, (2S,4R)-4-Hydroxypyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester, (2S,4R)-4-hydroxy-pyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester, (2S,4R)-N-tert-Butoxycarbonyl-4-hydroxyproline, (4R)-1-(tert-Butoxycarbonyl)-4-hydroxy-<span class="text-smallcaps">L</span>-proline, (4R)-1-(tert-butoxycarbonyl)-4-hydroxy-L-proline, 1,2-Pyrrolidinedicarboxylic acid, 4-hydroxy-, 1-(1,1-dimethylethyl) ester, (2S,4R)-, 1,2-Pyrrolidinedicarboxylic acid, 4-hydroxy-, 1-(1,1-dimethylethyl) ester, (2S-trans)-, 1,2-Pyrrolidinedicarboxylic acid, 4-hydroxy-, 1-tert-butyl ester, <span class="text-smallcaps">L</span>-, 1-(1,1-Dimethylethyl) (2S,4R)-4-hydroxy-1,2-pyrrolidinedicarboxylate, 1-(Tert-Butoxycarbonyl)-4-Hydroxyproline, 1-(tert-Butoxycarbonyl)-(2S,4R)-4-hydroxypyrrolidine-2-carboxylic acid, 4-Hydroxy-pyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester, BOC-4-Hydroxy-L-Proline, Boc-<span class="text-smallcaps">L</span>-trans-γ-hydroxyproline, Boc-Hyp-OH, Boc-L-Hyp-OHN-(tert-Butoxycarbonyl)-L-4-hydroxyproline, Boc-trans-4-hydroxy-L-proline, Boc-trans-Hydroxy-<span class="text-smallcaps">L</span>-proline, N-(tert-Butoxycarbonyl)-4-hydroxy-<span class="text-smallcaps">L</span>-proline, N-(tert-Butoxycarbonyl)hydroxy-<span class="text-smallcaps">L</span>-proline, N-BOC-trans-4-hydroxy-L-proline, N-Boc-trans-4-hydroxy-<span class="text-smallcaps">L</span>-proline, N-T-bocl-hydroxyproline, N-tert-Butoxycarbonyl trans-4-hydroxy-<span class="text-smallcaps">L</span>-proline, N-tert-Butoxycarbonyl-(4R)-4-hydroxy-<span class="text-smallcaps">L</span>-proline, trans-1-(tert-Butoxycarbonyl)-4-hydroxy-<span class="text-smallcaps">L</span>-proline, 1,2-Pyrrolidinedicarboxylic acid, 4-hydroxy-, 1-tert-butyl ester, L-

Beschreibung

Applications boc-trans-Hydroxy-L-proline is used in the preparation of hydroxyproline derivatives. boc-trans-Hydroxy-L-proline is an intermediate in the synthesis of Fosinopril-d5 Sodium Salt (F727803), the labeled analogue of Fosinopril Sodium Salt (F727800), a phosphinic acid containing angiotensin converting enzyme (ACE) inhibitor. Antihypertensive.
References Nakanishi, K., et. al.: Peptide Sci., 47, 197 (2010); Singhvi, S.M., et al.: Br. J. Clin. Pharmacol., 25, 9 (1988); Sullivan, P.A., et al.: Am. J. Hypertension, 1, 280S (1988)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 231.25
• Formel: C₁₀H₁₇NO₅
• Farbe/Form: Neat
• InChl: InChI=1S/C10H17NO5/c1-10(2,3)16-9(15)11-5-6(12)4-7(11)8(13)14/h6-7,12H,4-5H2,1-3H3,(H,13,14)/t6-,7+/m1/s1
• InChI Key: InChIKey=BENKAPCDIOILGV-RQJHMYQMSA-N
• SMILES: CC(C)(C)OC(=O)N1C[C@H](O)C[C@H]1C(=O)O