7-[2-Hydroxy(propyl-d6)]guanine

CAS: 1346599-30-1

Ref. TR-H952592

Produktinformation

• Name: 7-[2-Hydroxy(propyl-d6)]guanine
• Synonyme: 2-Amino-1,7-dihydro-7-[2-hydroxy(propyl-d6)]-6H-purin-6-one, N7-[2-Hydroxy(propyl-d6)]guanine
• Marke: TRC
• Beschreibung: Applications A labelled major adduct from alkylation of DNA by the genotoxic carcinogen, propylene oxide. Molecular dosimetry studies are used to find the amount present in tissues of F344 rats after inhalation exposure to propylene oxideReferences Rios-Blanco, M.N. et al.: Carcinogen., 24, 1233 (2003); Segerback, D. et al.: Chem.-Biol. Inter., 115, 229 (1998)

Chemische Eigenschaften

• Molekulargewicht: 215.24
• Formel: C₈H₅D₆N₅O₂
• Farbe/Form: Neat
• InChl: InChI=1S/C8H11N5O2/c1-4(14)2-13-3-10-6-5(13)7(15)12-8(9)11-6/h3-4,14H,2H2,1H3,(H3,9,11,12,15)
• InChI Key: InChIKey=JVWVMKYNORDKGP-DEGIAHCOSA-N
• SMILES: [2H]C([2H])([2H])C([2H])(O)C([2H])([2H])n1cnc2nc(N)[nH]c(=O)c21