(S)-9-[2-(Hydroxypropyl] Adenine

CAS: 14047-27-9

Ref. TR-H952690

Produktinformation

• Name: (S)-9-[2-(Hydroxypropyl] Adenine
• Synonyme: 9-[(2S)-2-Hydroxypropyl]adenine, L-(+)-9-(2-Hydroxypropyl)adenine, (aS)-6-Amino-a-methyl-9H-purine-9-ethanol, (S)-(-)-9-(2-Hydroxypropyl)Adenine, (S)-1-(6-amino-9H-purin-9-yl)propan-2-ol, (αS)-6-Amino-α-methyl-9H-purine-9-ethanol, 1-(6-Amino-9H-purin-9-yl)-2-propanol, 9H-Purine-9-ethanol, 6-amino-α-methyl-, (S)-, 9H-Purine-9-ethanol, 6-amino-α-methyl-, (αS)-, 9H-Purine-9-ethanol, 6-amino-α-methyl-, <span class="text-smallcaps">L</span>-, <span class="text-smallcaps">L</span>-(+)-9-(2-Hydroxypropyl)adenine
• CAS: 14047-27-9

Beschreibung

Applications (S)-9-[2-(Hydroxypropyl] Adenine is an inhibitor of adenosine deaminase. (S)-9-[2-(Hydroxypropyl] Adenine is used in the preparation of antiviral acyclic nucleoside thiophosphonates such as (S)-Tenofovir Disoproxil Fumarate (T018506).
References Roux, L. et al.: Eur. J. Med. Chem., 63, 869 (2013); Schaeffer, H. et al.: J. Med. Chem., 15, 456 (1972); Schaeffer, H. & Vince, R.: J. Med. Chem., 10, 689 (1967)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 193.206
• Formel: C₈H₁₁N₅O
• Farbe/Form: Off White Solid
• InChl: InChI=1S/C8H11N5O/c1-5(14)2-13-4-12-6-7(9)10-3-11-8(6)13/h3-5,14H,2H2,1H3,(H2,9,10,11)/t5-/m0/s1
• InChI Key: InChIKey=MJZYTEBKXLVLMY-YFKPBYRVSA-N
• SMILES: C[C@H](O)Cn1cnc2c(N)ncnc21