N-​(4-​(2-​Hydroxy-​3-​(isopropylamino)​propoxy)​phenyl)​butyramide Hydrochloride

CAS: 1432053-72-9

Ref. TR-H957145

Produktinformation

• Name: N-​(4-​(2-​Hydroxy-​3-​(isopropylamino)​propoxy)​phenyl)​butyramide Hydrochloride
• Synonyme: Acebutolol Hydrochloride Imp. E (EP), Acebutolol Imp. E (EP), N-[4-[(2RS)-2-Hydroxy-3-[(1-methylethyl)amino]propoxy]phenyl]butanamide Hydrochloride, Acebutolol Hydrochloride Imp. E (EP) as Hydrochloride, Acebutolol Hydrochloride Impurity E as Hydrochloride, Acebutolol Impurity E as Hydrochloride

Beschreibung

Impurity Acebutolol EP Impurity E
Applications N-​(4-​(2-​Hydroxy-​3-​(isopropylamino)​propoxy)​phenyl)​butyramide Hydrochloride is an impurity of Acebutolol (A123800), a cardioselective β-adrenergic blocker. Antihypertensive; antianginal; antiarrhythmic (class II). (Acebutolol EP Impurity E)
References Cuthbert, O.A., et al.: Br. J. Pharmacol., 43, 639 (1971), Singh, B.N., et al.: Drugs, 29, 531 (1985), Foster, R.T., et al.: Anal. Profiles Drug Subs., 19, 1 (1990),

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 330.85
• Formel: C₁₆H₂₆N₂O₃·ClH
• Farbe/Form: Off-White
• InChl: 1-5(2,3)4/h5-12,14,17-18H,13,15H2,1-4H3, InChI=1S/C21H27N3.H3O4P/c1-17(2)24(18(3)4)15-13-21(16-22,19-10-6-5-7-11-19)20-12-8-9-14-23-20, (H3,1,2,3,4)
• InChI Key: InChIKey=HQQSBEDKMRHYME-UHFFFAOYSA-N
• SMILES: CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCN(C)CC3)cc21.CS(=O)(=O)O