3a-Hydroxy Tibolone

CAS: 100239-44-9

Ref. TR-H964250

Produktinformation

• Name: 3a-Hydroxy Tibolone
• Synonyme: (3R,7R,8R,9S,13S,14S,17R)-17-ethynyl-7,13-dimethyl-2,3,4,6,7,8,9,11,12,14,15,16-dodecahydro-1H-cyclopenta[a]phenanthrene-3,17-diol, (3A,7A,17A)-3,17-Dihydroxy-7-Methyl-19-Norpregn-5(10)-En-20-Yl-3-One, (3α,7α,17α)-7-Methyl-19-norpregn-5(10)-en-20-yne-3,17-diol, 19-Norpregn-5(10)-en-20-yne-3,17-diol, 7-methyl-, (3α,7α,17α)-, 3-alpha-Hydroxytibolone, Org 4094
• CAS: 100239-44-9

Beschreibung

Applications A metabolite of Tibolone. A synthetic steroid with weak estrogenic, androgenic and progestogenic activity. A pharamceutical used in the treatment of menopausal syndrome.
References Belman, S., et al.: Cancer Res., 32, 450 (1972), Shirahashi, H., et al.: Chem. Pharm. Bull., 41, 1664 (1993), Hoyte, R., et al.: Steroids, 58, 13 (1993), Sandker, G., et al.: Xenobiotica, 24, 143 (1994), Colombo, D., et al.: Eur. J. Med. Chem., 40, 69 (2005),

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 314.46
• Formel: C₂₁H₃₀O₂
• Farbe/Form: White To Off-White
• InChl: InChI=1S/C21H30O2/c1-4-21(23)10-8-18-19-13(2)11-14-12-15(22)5-6-16(14)17(19)7-9-20(18,21)3/h1,13,15,17-19,22-23H,5-12H2,2-3H3/t13-,15-,17-,18+,19-,20+,21+/m1/s1
• SMILES: C#C[C@]1(O)CC[C@H]2[C@H]3[C@H](CC[C@@]21C)C1=C(C[C@H](O)CC1)C[C@H]3C