5-Hydroxy-1-(3-methoxy-4-((tetrahydro-2H-pyran-2-yl)oxy)phenyl)decan-3-one

Ref. TR-H973165

Produktinformation

• Name: 5-Hydroxy-1-(3-methoxy-4-((tetrahydro-2H-pyran-2-yl)oxy)phenyl)decan-3-one
• Synonyme: 5-hydroxy-1-[3-methoxy-4-(oxan-2-yloxy)phenyl]decan-3-one
• Marke: TRC
• Beschreibung: Applications 5-Hydroxy-1-(3-methoxy-4-((tetrahydro-2H-pyran-2-yl)oxy)phenyl)decan-3-one is an intermediate used in the synthesis of [6]-Shogaol (S357800), which is an aromatic constituent of ginger and the chain-dehydroxylated analog of [6]-Gingerol. [6]-Shogaol has activity very similar to [6]-Gingerol and produced an inhibition of spontaneous motor activity, antipyretic and analgesic effects, and prolonged hexobarbital-induced sleeping time. [6]-Shogaol also has potent antitussive activity and affected the cortical EEG.References Suekawa, M. et al.: J. Pharm-Dyn., 7, 836 (1984); Yoshikawa, M. et al.: Chem. Pharmac. Bull., 40, 2239 (1992)

Chemische Eigenschaften

• Molekulargewicht: 378.502
• Formel: C₂₂H₃₄O₅
• Farbe/Form: Neat
• InChl: InChI=1S/C22H34O5/c1-3-4-5-8-18(23)16-19(24)12-10-17-11-13-20(21(15-17)25-2)27-22-9-6-7-14-26-22/h11,13,15,18,22-23H,3-10,12,14,16H2,1-2H3
• InChI Key: InChIKey=HRSHHVJCQQBBSP-UHFFFAOYSA-N
• SMILES: CCCCCC(O)CC(=O)CCc1ccc(OC2CCCCO2)c(OC)c1