Hydroxy Velpatasvir

Ref. TR-H996015

Produktinformation

• Name: Hydroxy Velpatasvir
• Synonyme: Methyl {(2S)-1-[(2S,5S)-2-(9-{2-[(2S,4S)-1-{(2R)-2-[(methoxycarbonyl)amino]-2-phenylacetyl}-4-(methoxymethyl) pyrrolidin-2-yl]-1H-imidazol-5-yl]-11-hydroxy-1,11-dihydroisochromeno [4’,3’:6,7]naphtho[1,2-d]imidazol-2-yl)-5-methylpyrrolidin-1-yl]-3-methyl-1-oxobutan-2-yl}carbamate, Velpatasvir Impurity E
• Marke: TRC
• Beschreibung: Applications Hydroxy Velpatasvir is an impurity of antivaral drug Velpatasvir (V116000), which is a HCV NS5A inhibitor used to treat Hepatitis C.References Feld, J. J., et al.: N. Engl. J. Med. 373, 2599 (2015); Gane, E. J., et al.: Gastroenterol., 151, 448 (2016)

Chemische Eigenschaften

• Molekulargewicht: 899.001
• Formel: C₄₉H₅₄N₈O₉
• Farbe/Form: Neat
• InChl: InChI=1S/C49H54N8O9/c1-25(2)40(54-48(61)64-5)46(59)57-26(3)12-17-37(57)44-51-35-16-14-29-19-33-31-15-13-30(20-34(31)47(60)66-39(33)21-32(29)42(35)53-44)36-22-50-43(52-36)38-18-27(24-63-4)23-56(38)45(58)41(55-49(62)65-6)28-10-8-7-9-11-28/h7-11,13-16,19-22,25-27,37-38,40-41,47,60H,12,17-18,23-24H2,1-6H3,(H,50,52)(H,51,53)(H,54,61)(H,55,62)/t26-,27-,37-,38-,40-,41+,47?/m0/s1
• InChI Key: InChIKey=ZGMXQRKKSGHCTO-MZLBGWRESA-N
• SMILES: COC[C@H]1C[C@@H](c2ncc(-c3ccc4c(c3)C(O)Oc3cc5c(ccc6nc([C@@H]7CC[C@H](C)N7C(=O)[C@@H](NC(=O)OC)C(C)C)[nH]c65)cc3-4)[nH]2)N(C(=O)[C@H](NC(=O)OC)c2ccccc2)C1