2-Imino-4-thiobiuret

CAS: 2114-02-5

Ref. TR-I449995

Produktinformation

• Name: 2-Imino-4-thiobiuret
• Synonyme: (Aminoiminomethyl)thiourea, 1-Amidino-2-thiourea, 1-Amidinothiourea, ASU, Amidinothiourea, Amino[[amino(imino)methyl]amino]thioxomethane, Guanylthiourea, Guthimin, Gutimine, N-(Diaminomethylene)thiourea, N-Amidinothiourea, NSC 55743, Thiodicyanodiamidine, (Diaminomethylidene)thiourea, 1-(Diaminomethylidene)Thiourea, Aminoiminoethyl thiourea, N-(Aminoiminomethyl)thiourea, Thiourea, (aminoiminomethyl)-, Thiourea, N-(aminoiminomethyl)-, Urea, 1-amidino-2-thio-, amino-N-(diaminomethylidene)thioxomethanaminium

Beschreibung

Applications 2-Imino-4-thiobiuret is used in the design and synthesis of guanylthiourea derivatives which are potential inhibitors of plasmodium falciparum dihydrofolate reductase enzyme. 2-Imino-4-thiobiuret is also used as a reagent in recyclization reactions of N-arylmaleimides with polynucleophilic compounds.
References Adane, L., et al.: Bioorgan. Med. Chem. Lett., 24, 613 (2014); Zorina, A., et al.: Chem. Heterocyc. Compd., 50, 1541(2015)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 118.16
• Formel: C₂H₆N₄S
• Farbe/Form: Neat
• InChl: InChI=1S/C2H6N4S/c3-1(4)6-2(5)7/h(H6,3,4,5,6,7)
• InChI Key: InChIKey=OKGXJRGLYVRVNE-UHFFFAOYSA-N
• SMILES: N=C(N)NC(N)=S