Ivabradine N-oxide

CAS: 2511244-97-4

Ref. TR-I940520

Produktinformation

• Name: Ivabradine N-oxide
• Synonyme: 3-(7,8-Dimethoxy-2-oxo-1,2,4,5-tetrahydro-3H-benzo[d]azepin-3-yl)-N-(((S)-3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methyl)-N-methylpropan-1-amine Oxide, 2H-3-Benzazepin-2-one, 3-[3-[[[(7S)-3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl]methyloxidoamino]propyl]-1,3,4,5-tetrahydro-7,8-dimethoxy- (ACI), 3-[3-[[[(7S)-3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl]methylox

Beschreibung

Impurity Ivabradine N-Oxide Impurity
Applications Ivabradine N-oxide is a derivative of Ivabradine (I940500), which is a selective bradycardic agent with direct effect on the pacemaker If current of the sinoatrial node. Antianginal.
References Thollon,C., et al.: Br. J. Pharmacol., 112, 37 (1994), Ragueneau, I., et al.: Clin. Pharmacol. Ther., 64, 192 (1998), Borer, J.S., et al.: Circulation, 107, 817 (2003), DiFrancesco, D., et al.: Drugs, 64, 1757 (2004),

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 484.584
• Formel: C₂₇H₃₆N₂O₆
• Farbe/Form: Neat
• InChl: InChI=1S/C27H36N2O6/c1-29(31,17-21-11-20-14-25(34-4)26(35-5)16-22(20)21)10-6-8-28-9-7-18-12-23(32-2)24(33-3)13-19(18)15-27(28)30/h12-14,16,21H,6-11,15,17H2,1-5H3/t21-,29?/m1/s1
• InChI Key: InChIKey=GJZRGCOPHQZQGJ-QYWNIODHSA-N
• SMILES: COc1cc2c(cc1OC)CC(=O)N(CCC[N+](C)([O-])C[C@H]1Cc3cc(OC)c(OC)cc31)CC2