K-41498 TFA Salt

CAS: 434938-41-7

Ref. TR-K003000

Produktinformation

• Name: K-41498 TFA Salt
• Synonyme: D-Phenylalanyl-L-histidyl-L-leucyl-L-leucyl-L-arginyl-L-lysyl-L-norleucyl-L-isoleucyl-L-α-glutamyl-L-isoleucyl-L-α-glutamyl-L-lysyl-L-glutaminyl-L-α-glutamyl-L-lysyl-L-α-glutamyl-L-lysyl-L-glutaminyl-L-glutaminyl-L-alanyl-L-alanyl-L-asparaginyl-L-asparaginyl-L-arginyl-L-leucyl-L-leucyl-L-leucyl-L-α-aspartyl-L-threonyl-L-Isoleucinamide TFA Salt
• Marke: TRC
• Beschreibung: Applications K-41498 is a highly selective CRF2 receptor antagonist and used to treat hypertension in rodents (1,2).References (1) Lawrence, A. et al.: Br. J. Pharmacol., 136, 896 (2002) (2) Rühmann, A. et al.: Peptides., 23, 453 (2002)

Chemische Eigenschaften

• Molekulargewicht: 3746.24
• Formel: C₁₆₂H₂₇₆N₄₈O₄₆·C₂HF₃O₂
• Farbe/Form: Neat
• InChl: InChI=1S/C158H270N46O44.C2HF3O2/c1-21-25-41-93(179-133(225)94(42-29-33-62-159)180-137(229)98(46-37-66-174-157(169)170)184-146(238)107(68-79(5)6)196-149(241)110(71-82(11)12)199-151(243)112(74-91-77-173-78-176-91)194-131(223)92(163)73-90-39-27-26-28-40-90)144(236)202-125(85(16)23-3)155(247)192-106(54-61-122(216)217)145(237)203-126(86(17)24-4)154(246)191-105(53-60-121(214)215)143(235)183-96(44-31-35-64-161)135(227)188-102(50-57-117(166)208)140(232)190-104(52-59-120(212)213)142(234)182-97(45-32-36-65-162)136(228)189-103(51-58-119(210)211)141(233)181-95(43-30-34-63-160)134(226)187-101(49-56-116(165)207)139(231)186-100(48-55-115(164)206)132(224)178-87(18)129(221)177-88(19)130(222)193-113(75-118(167)209)152(244)185-99(47-38-67-175-158(171)172)138(230)195-108(69-80(7)8)147(239)197-109(70-81(9)10)148(240)198-111(72-83(13)14)150(242)200-114(76-123(218)219)153(245)204-127(89(20)205)156(248)201-124(128(168)220)84(15)22-2;3-2(4,5)1(6)7/h26-28,39-40,77-89,92-114,124-127,205H,21-25,29-38,41-76,159-163H2,1-20H3,(H2,164,206)(H2,165,207)(H2,166,208)(H2,167,209)(H2,168,220)(H,173,176)(H,177,221)(H,178,224)(H,179,225)(H,180,229)(H,181,233)(H,182,234)(H,183,235)(H,184,238)(H,185,244)(H,186,231)(H,187,226)(H,188,227)(H,189,228)(H,190,232)(H,191,246)(H,192,247)(H,193,222)(H,194,223)(H,195,230)(H,196,241)(H,197,239)(H,198,240)(H,199,243)(H,200,242)(H,201,248)(H,202,236)(H,203,237)(H,204,245)(H,210,211)(H,212,213)(H,214,215)(H,216,217)(H,218,219)(H4,169,170,174)(H4,171,172,175);(H,6,7)/t84-,85-,86-,87-,88-,89+,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,111-,112-,113-,114-,124-,125-,126-,127-;/m0./s1/i/hD
• InChI Key: InChIKey=PGEYFCBAWGQSGT-GBXIJSLDSA-N
• SMILES: NC(=O)[C@H](F)C[C@H](N)C(=O)O