Kartogenin-d4

CAS: 4727-31-5

Ref. TR-K139802

Produktinformation

• Name: Kartogenin-d4
• Synonyme: 2,3,4,5-tetradeuterio-6-[(4-phenylphenyl)carbamoyl]benzoic acid

Beschreibung

Applications Labelled Kartogenin (K139800). Kartogenin is a potent, selective, and non-cytotoxic downstream RUNX1 and RUNX2 modulator. Kartogenin causes mesenchymal stem cells found in joints to differentiate into chondrocyte cells that can build cartilage where it has been destroyed.
References Ruschig, H., et al.: Arzneim.-Forsch. Drug Res., 23, 1745 (1973), Hartmann, R., et al.: J. Med. Chem., 35, 2210 (1992), Kishida., et al.: Biochemistry, 45, 783 (2006),

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 321.363
• Formel: C₂₀D₄H₁₁NO₃
• Farbe/Form: Neat
• InChl: InChI=1S/C20H15NO3/c22-19(17-8-4-5-9-18(17)20(23)24)21-16-12-10-15(11-13-16)14-6-2-1-3-7-14/h1-13H,(H,21,22)(H,23,24)/i4D,5D,8D,9D
• InChI Key: InChIKey=SLUINPGXGFUMLL-DOGSKSIHSA-N
• SMILES: [2H]c1c([2H])c([2H])c(C(=O)Nc2ccc(-c3ccccc3)cc2)c(C(=O)O)c1[2H]