Kartogenin-d4

CAS: 4727-31-5

Ref. TR-K139802

Produktinformation

• Name: Kartogenin-d4
• Synonyme: 2-[([1,1'-Biphenyl]-4-ylamino)carbonyl]benzoic Acid-d4, 2-[(Biphenyl-4-yl)carbamoyl]benzoic Acid-d4, 4'-Phenylphthalanilic Acid-d4, KGN-d4
• CAS: 4727-31-5

Beschreibung

Applications Labelled Kartogenin (K139800). Kartogenin is a potent, selective, and non-cytotoxic downstream RUNX1 and RUNX2 modulator. Kartogenin causes mesenchymal stem cells found in joints to differentiate into chondrocyte cells that can build cartilage where it has been destroyed.
References Ruschig, H., et al.: Arzneim.-Forsch. Drug Res., 23, 1745 (1973), Hartmann, R., et al.: J. Med. Chem., 35, 2210 (1992), Kishida., et al.: Biochemistry, 45, 783 (2006),

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 321.363
• Formel: C₂₀H₁₁D₄NO₃
• InChl: InChI=1S/C20H15NO3/c22-19(17-8-4-5-9-18(17)20(23)24)21-16-12-10-15(11-13-16)14-6-2-1-3-7-14/h1-13H,(H,21,22)(H,23,24)/i4D,5D,8D,9D
• InChI Key: InChIKey=SLUINPGXGFUMLL-DOGSKSIHSA-N
• SMILES: [2H]c1c([2H])c([2H])c(C(=O)Nc2ccc(-c3ccccc3)cc2)c(C(=O)O)c1[2H]