rac-Kavain-d3

CAS: 3155-48-4

Ref. TR-K145492

Produktinformation

• Name: rac-Kavain-d3
• Synonyme: 5,6-Dihydro-4-methoxy-6-[(1E)-2-phenylethenyl]-2H-pyran-2-one-d3, DL-Kawain-d3, dl-Kavain-d3
• Marke: TRC

Beschreibung

Stability Light and Moisture Sensitive
Applications Isotope Labelled analogue of rac-Kavain (K145490), the main kavalactone found in the roots of the kava plant. Kavain is known to exhibit anticonvulsive properties by attenuating vascular smooth muscle contraction through interactions with voltage-dependent sodium and calcium channels. rac-Kavain was shown in recent research to exhibit protective properties on anaerobic glycolysis, ATP content and intracellular calcium and sodium of anoxic brain vesicles.
References Gleitz, J., et al: Neuropharmacol., 35, 1743 (1997); Hashimoto, T., et al.: Phytomedicine, 10, 309 (2003); Mulholland, P.J., et al.: Brain. Res., 945, 106 (2002);

Chemische Eigenschaften

• Molekulargewicht: 233.28
• Formel: C₁₄D₃H₁₁O₃
• Farbe/Form: Neat
• InChl: InChI=1S/C14H14O4/c1-17-13-8-12(18-14(16)9-13)7-4-10-2-5-11(15)6-3-10/h2-7,9,12,15H,8H2,1H3/b7-4+
• InChI Key: InChIKey=XEAQIWGXBXCYFX-MXMZWNBPSA-N
• SMILES: [2H]C([2H])([2H])OC1=CC(=O)OC(/C=C/c2ccccc2)C1