10-Ketonaloxone 3-Methyl Ether

CAS: 294175-45-4

Ref. TR-K425105

Produktinformation

• Name: 10-Ketonaloxone 3-Methyl Ether
• Synonyme: (5alpha)-4,5-Epoxy-14-hydroxy-3-methoxy-17-(2-propenyl)-morphinan-6,10-dione

Beschreibung

Applications 10-Ketonaloxone 3-Methyl Ether is an intermediate in the synthesis of 10-Oxo Naloxone (O858150). 10-Oxo Naloxone is a keto analog of the opioid antagonist Naloxone (N285000).
References Jasinski, D.R., et al.: J. Pharmacol. Exp. Ther., 157, 420 (1967); McNicholas, L.F., et al.: Drugs, 27, 81 (1984); Hasson, M.M.A., et al.: Anal. Profiles Drug Subs., 14, 453 (1985); Stowe, C., et al.: Ann. Pharmacother., 27, 447 (1993)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 355.38
• Formel: C₂₀H₂₁NO₅
• Farbe/Form: Neat
• InChl: InChI=1S/C20H21NO5/c1-3-9-21-10-8-19-14-11-4-5-13(25-2)16(14)26-18(19)12(22)6-7-20(19,24)17(21)15(11)23/h3-5,17-18,24H,1,6-10H2,2H3/t17-,18+,19+,20-/m1/s1
• InChI Key: InChIKey=OHQBKEATFCQVAZ-FUMNGEBKSA-N
• SMILES: C=CCN1CC[C@]23c4c5ccc(OC)c4O[C@H]2C(=O)CC[C@@]3(O)[C@H]1C5=O