KN-93

CAS: 139298-40-1

Ref. TR-K653000

Produktinformation

• Name: KN-93
• Synonyme: N-[2-[[[3-(4-Chlorophenyl)-2-propen-1-yl]methylamino]methyl]phenyl]-N-(2-hydroxyethyl)-4-methoxybenzenesulfonamide, 2-[N-(2-Hydroxyethyl)-N-(4-Methoxybenzenesulfonyl)]Amino-N-(4-Chlorocinnamyl)-N-Methylbenzylamine, Benzenesulfonamide, N-[2-[[[3-(4-chlorophenyl)-2-propen-1-yl]methylamino]methyl]phenyl]-N-(2-hydroxyethyl)-4-methoxy-, Benzenesulfonamide, N-[2-[[[3-(4-chlorophenyl)-2-propenyl]methylamino]methyl]phenyl]-N-(2-hydroxyethyl)-4-methoxy-, Kn-93, Water-Soluble, Methoxybenzene-Sulfonamide, N-[2-({[(2E)-3-(4-chlorophenyl)prop-2-en-1-yl](methyl)amino}methyl)phenyl]-N-(2-hydroxyethyl)-4-methoxybenzenesulfonamide, N-[2-N-4-Chlorocinnamyl-N-Methylaminomethylphenyl]-N-[2-Hydroxyethyl]-4-Methoxybenzenesulfonamide, N-[2-[[[3-(4'-Chlorophenyl)-2-Propenyl]Methylamino]Methyl]Phenyl]-N-(2-Hydroxyethyl)-4'-Methoxy-Benzenesulfonamide Phosphate, N-[2-[[[3-(4-Chlorophenyl)-2-Propenyl]Methylamino]Methyl]Phenyl]-N-(2-Hydroxyethyl)-4-Methoxybenzenesulphonamide, N-[2-[[[3-(4-Chlorophenyl)-2-propenyl]methylamino]methyl]phenyl]-N-(2-hydroxyethyl)-4-methoxybenzenesulfonamide

Beschreibung

Applications A potent and selective inhibitor of Ca2+/Calmoduline-dependent protein kinase II (CaMKII).
References Linseman, D., et al.: J. Biol. Chem., 278, 41472 (2003), Yu, J., et al.: Brain Res., 1238, 143 (2008),

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 501.04
• Formel: C₂₆H₂₉ClN₂O₄S
• Farbe/Form: White to Off-White Solid
• InChl: InChI=1S/C26H29ClN2O4S/c1-28(17-5-6-21-9-11-23(27)12-10-21)20-22-7-3-4-8-26(22)29(18-19-30)34(31,32)25-15-13-24(33-2)14-16-25/h3-16,30H,17-20H2,1-2H3/b6-5+
• InChI Key: InChIKey=LLLQTDSSHZREGW-AATRIKPKSA-N
• SMILES: COc1ccc(S(=O)(=O)N(CCO)c2ccccc2CN(C)CC=Cc2ccc(Cl)cc2)cc1