Lapatinib-d7 Sulfoxide Dihydrochloride

CAS: 1275595-86-2, 1611495-33-0

Ref. TR-L175812

Produktinformation

• Name: Lapatinib-d7 Sulfoxide Dihydrochloride
• Synonyme: N-​[3-​Chloro-​4-​[(3-​fluorophenyl)​methoxy]​phenyl]​-​6-​[5-​[[[2-​(methylsulfinyl)​ethyl]​amino]​methyl]​-​2-​furanyl]​-4-​quinazolinamine-d7 Dihydrochloride
• Marke: TRC
• Beschreibung: Applications Lapatinib-d7 Sulfoxide Dihydrochloride is a by-product during the synthesis of Lapatinib-d7 Dihydrochloride (L175807), a labeled Lapatinib (L175800), a reversible dual inhibitor of ErbB1 and ErbB2 tyrosine kinases. Antineoplastic.References Kim, T.E., et al.: Drugs, 6, 886 (2003); Wood, E.R., et al.: Cancer Res., 64, 6652 (2004); Spector, N.L., et al.: J. Clin. Oncol., 23, 2502 (2005)

Chemische Eigenschaften

• Molekulargewicht: 645.02
• Formel: C₂₉H₁₉D₇ClFN₄O₃S·2(HCl)
• Farbe/Form: Neat
• InChl: InChI=1S/C29H26ClFN4O3S.2ClH/c1-39(36)12-11-32-16-23-7-10-27(38-23)20-5-8-26-24(14-20)29(34-18-33-26)35-22-6-9-28(25(30)15-22)37-17-19-3-2-4-21(31)13-19;;/h2-10,13-15,18,32H,11-12,16-17H2,1H3,(H,33,34,35);2*1H/i1D3,11D2,12D2