Levomefolic Acid-13C,d3

CAS: 1356019-94-7

Ref. TR-L375732

Produktinformation

• Name: Levomefolic Acid-13C,d3
• Synonyme: N-[4-[[[(6S)-2-Amino-3,4,5,6,7,8-hexahydro-5-(methyl-13C,d3)-4-oxo-6-pteridinyl]methyl]amino]benzoyl]-L-glutamic acid, (6S)-5-(Methyl-13C,d3)tetrahydrofolic acid, 5-(Methyl-13C,d3)-(6S)-tetrahydrofolic acid, L-Methylfolate-13C,d3, Levomefolic acid (N-methyl-13C,d3), l-N5-(Methyl-13C,d3)-L-tetrahydrofolic acid

Beschreibung

Applications A labelled active form of folic acid used at the cellular level for DNA reproduction, the cysteine cycle and the regulation of homocysteine among other functions. It is a coenzymated form of folic acid. It has been proposed for treatment of cardiovascular disease.
References Willems, F. et al.: Br. J. Pharmacol., 145, 823 (2004); Prinz-Langhebohi, R.: et al., Br. J. Pharmacol., 158, 2014 (2009); Wright, A. et al.: Brit, J. Nutrit., 103, 724 (2010)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 463.47
• Formel: CC₁₉H₃H₂₂N₇O₆
• Farbe/Form: Beige
• InChl: InChI=1S/C20H25N7O6/c1-27-12(9-23-16-15(27)18(31)26-20(21)25-16)8-22-11-4-2-10(3-5-11)17(30)24-13(19(32)33)6-7-14(28)29/h2-5,12-13,22H,6-9H2,1H3,(H,24,30)(H,28,29)(H,32,33)(H4,21,23,25,26,31)/t12-,13-/m0/s1/i1+1D3
• InChI Key: InChIKey=ZNOVTXRBGFNYRX-OWXPWHJLSA-N
• SMILES: [2H][13C]([2H])([2H])N1c2c([nH]c(N)nc2=O)NC[C@@H]1CNc1ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)cc1