(R)-8-(3-Aminopiperidin-1-yl)-3,7-dimethyl-1-((4-methylquinazolin-2-yl)methyl)-1H-purine-2,6(3H,7H)-dione

CAS: 1339955-47-3

Ref. TR-L465901

Produktinformation

• Name: (R)-8-(3-Aminopiperidin-1-yl)-3,7-dimethyl-1-((4-methylquinazolin-2-yl)methyl)-1H-purine-2,6(3H,7H)-dione
• Synonyme: 8-[(3R)-3-Amino-1-piperidinyl]-3,7-dihydro-3,7-dimethyl-1-[(4-methyl-2-quinazolinyl)methyl]-1H-purine-2,6-dione, Linagliptin Impurity 2
• Marke: TRC
• Beschreibung: Applications 8-[(3R)-3-Amino-1-piperidinyl]-3,7-dihydro-3,7-dimethyl-1-[(4-methyl-2-quinazolinyl)methyl]-1H-purine-2,6-dione is an impurity of Linagliptin (L465900). Linagliptin is a novel potent and selective dipeptidyl peptidase-4 (DPP-4) inhibitor with potential use in the treatment of type 2 diabetes.References Prabavathy, N. et al.: Int. J. Pharm. Bio. Sci., 2, 438 (2011); Deacon, C.F.: Diab. Obes. Metab., 13, 7 (2011)

Chemische Eigenschaften

• Molekulargewicht: 434.494
• Formel: C₂₂H₂₆N₈O₂
• Farbe/Form: Neat
• InChl: InChI=1S/C22H26N8O2/c1-13-15-8-4-5-9-16(15)25-17(24-13)12-30-20(31)18-19(28(3)22(30)32)26-21(27(18)2)29-10-6-7-14(23)11-29/h4-5,8-9,14H,6-7,10-12,23H2,1-3H3/t14-/m1/s1
• InChI Key: InChIKey=IQLUHPBHOFYRAO-CQSZACIVSA-N
• SMILES: Cc1nc(Cn2c(=O)c3c(nc(N4CCC[C@@H](N)C4)n3C)n(C)c2=O)nc2ccccc12