Lincomycin

CAS: 154-21-2

Ref. TR-L466230

Produktinformation

• Name: Lincomycin
• Synonyme: D-erythro-α-D-galacto-Octopyranoside, methyl 6,8-dideoxy-6-[[[(2S,4R)-1-methyl-4-propyl-2-pyrrolidinyl]carbonyl]amino]-1-thio-, D-erythro-D-galacto-Octopyranoside, methyl 6,8-dideoxy-6-(1-methyl-4-propyl-L-2-pyrrolidinecarboxamido)-1-thio-, trans-α- (8CI), D-erythro-α-D-galacto-Octopyranoside, methyl 6,8-dideoxy-6-[[(1-methyl-4-propyl-2-pyrrolidinyl)carbonyl]amino]-1-thio-, (2S-trans)-, Lincomycin (7CI), Methyl 6,8-dideoxy-6-[[[(2S,4R)-1-methyl-4-propyl-2-pyrrolidinyl]carbonyl]amino]-1-thio-D-erythro-α-D-galacto-octopyranoside, Cillimycin, Jiemycin, Lincolcina, Lincolnensin, Lincomycin A, Medoglycine, U 10,149A
• Marke: TRC
• Beschreibung: Impurity Clindamycin Phosphate EP Impurity AStability HygroscopicApplications Lincomycin (Clindamycin Phosphate EP Impurity A) is a lincosamide antibiotic that forms cross-links within the peptidyl transferase loop region of the 23S rRNA. Inhibits bacterial protein synthesis. Antibacterial.This compound is a contaminant of emerging concern (CECs).References Mason, D.J., et al.: Antimicrob. Agents Chemother., 555 (1962), Gray, et al.: Toxicol. Appl. Pharmacol., 6, 476 (1964), Muti, H.Y., et al.: Anal. Profiles Drug Subs. Excip., 23, 269 (1994),

Chemische Eigenschaften

• Molekulargewicht: 406.54
• Formel: C₁₈H₃₄N₂O₆S
• Farbe/Form: White To Off-White
• InChl: InChI=1S/C18H34N2O6S/c1-5-6-10-7-11(20(3)8-10)17(25)19-12(9(2)21)16-14(23)13(22)15(24)18(26-16)27-4/h9-16,18,21-24H,5-8H2,1-4H3,(H,19,25)/t9-,10-,11+,12-,13+,14-,15-,16-,18-/m1/s1
• InChI Key: InChIKey=OJMMVQQUTAEWLP-HYVSCUIGSA-N
• SMILES: CCC[C@@H]1CC(C(=O)N[C@H]([C@@H](C)O)[C@H]2O[C@H](SC)C(O)C(O)[C@H]2O)N(C)C1