Loratadine Impurity F

CAS: 125743-80-8

Ref. TR-L469580

Produktinformation

• Name: Loratadine Impurity F
• Synonyme: 1-Piperidinecarboxylic acid, 4-(8-chloro-11-fluoro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-, ethyl ester, 5H-Benzo[5,6]cyclohepta[1,2-b]pyridine, 1-piperidinecarboxylic acid deriv., Ethyl 4-(8-chloro-11-fluoro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-1-piperidinecarboxylate, Ethyl 4-[(11RS)-8-chloro-11-fluoro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl]piperidine-1-carboxylate
• Marke: TRC
• Beschreibung: Impurity Loratadine EP Impurity F; Loratadine USP Related Compound G ImpurityApplications Loratadine Impurity F (Loratadine EP Impurity F; Loratadine USP Related Compound G Impurity) is a fluorinated analog of Loratadine (L469575), which is a nonsedating-type histamine H1-receptor.References Bruttmann, G., et al.: J. Allergy Clin. Immunol., 83, 411 (1989), Haria, M., et al.: Drugs, 48, 617 (1994)

Chemische Eigenschaften

• Molekulargewicht: 402.89
• Formel: C₂₂H₂₄ClFN₂O₂
• Farbe/Form: White To Off-White
• InChl: InChI=1S/C22H24ClFN2O2/c1-2-28-21(27)26-12-9-17(10-13-26)22(24)19-8-7-18(23)14-16(19)6-5-15-4-3-11-25-20(15)22/h3-4,7-8,11,14,17H,2,5-6,9-10,12-13H2,1H3
• InChI Key: InChIKey=OVPFJWGOZPZTKG-UHFFFAOYSA-N
• SMILES: CCOC(=O)N1CCC(C2(F)c3ccc(Cl)cc3CCc3cccnc32)CC1