Loteprednol Etabonate

CAS: 82034-46-6

Ref. TR-L471400

Produktinformation

• Name: Loteprednol Etabonate
• Synonyme: Alrex, CDDD 5604, HGP 1, Lenoxin, Lotemax, P 5604, (11beta,17alpha)-17-[(ethoxycarbonyl)oxy]-11-hydroxy-3-oxo-Androsta-1,4-diene-17-carboxylic acid chloromethyl ester, Androsta-1,4-diene-17-carboxylic acid, 17-[(ethoxycarbonyl)oxy]-11-hydroxy-3-oxo-, chloromethyl ester, (11β,17α)-, Chloromethyl (8xi,9xi,11beta,14xi,17alpha)-17-[(ethoxycarbonyl)oxy]-11-hydroxy-3-oxoandrosta-1,4-diene-17-carboxylate, chloromethyl (11beta,17alpha)-17-[(ethoxycarbonyl)oxy]-11-hydroxy-3-oxoandrosta-1,4-diene-17-carboxylate, androsta-1,4-diene-17-carboxylic acid, 17-[(ethoxycarbonyl)oxy]-11-hydroxy-3-oxo-, chloromethyl ester, (8xi,9xi,11beta,14xi,17alpha)-, Loteprednol etabonate

Beschreibung

Applications An ophthalmic corticosteroid. Used as an anti-inflammatory.
References Alberth, M., et al.: J. Biopharm.Sci., 2, 115 (1991), Bodor, N., et al.: Pharm. Res., 9, 1275 (1992), Bartlett, J.D., et al.: J. Ocul. Pharmacol., 9, 157 (1993)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 466.95
• Formel: C₂₄H₃₁ClO₇
• Farbe/Form: White
• InChl: InChI=1S/C24H31ClO7/c1-4-30-21(29)32-24(20(28)31-13-25)10-8-17-16-6-5-14-11-15(26)7-9-22(14,2)19(16)18(27)12-23(17,24)3/h7,9,11,16-19,27H,4-6,8,10,12-13H2,1-3H3/t16-,17-,18-,19+,22-,23-,24-/m0/s1
• InChI Key: InChIKey=DMKSVUSAATWOCU-HROMYWEYSA-N
• SMILES: CCOC(=O)O[C@]1(C(=O)OCCl)CC[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@H]3[C@@H](O)C[C@@]21C