Loxoprofen

CAS: 68767-14-6

Ref. TR-L472905

Produktinformation

• Name: Loxoprofen
• Synonyme: 2-[4-[(2-oxocyclopentyl)methyl]phenyl]propanoic acid, 2-[4-(2-Oxo-Cyclopentylmethyl)-Phenyl]-Propionic Acid, 2-[4-[(2-Oxocyclopentan-1-Yl)Methyl]Phenyl]Propionic Acid, 2-[4-[(2-Oxocyclopentyl)methyl]phenyl]propionic acid, 2-{4-[(2-Oxocyclopentyl)Methyl]Phenyl}Propanoic Acid, A-Methyl-4-[(2-Oxocyclopentyl)Methyl]Benzeneacetic Acid, Alpha-Methyl-4-[(2-Oxocyclopentyl)Methyl]Benzeneacetic Acid, Benzeneacetic acid, α-methyl-4-[(2-oxocyclopentyl)methyl]-, Ioxoprofen, Koloxo, Loxoprofen Acid, ��-Methyl-4-[(2-Oxocyclopentyl)Methyl]Benzeneacetic Acid

Beschreibung

Applications Loxoprofen is a non-selective nonsteroidal anti-inflammatory drug (NSAID) that has been effective in reducing atherosclerosis in mice by reducing inflammation. Loxoprofen becomes active after metabolism in the body and inhibits the activation of cyclooxygenase.
References Masahide H. et al.: J Clin Biochem Nutr., 47, 138 (2010); Noguchi, M. et al.: Biolog. Pharmac. Bull., 28, 2075 (2005); Hyun, J. et al.: Arch. Pharm. Res., 24, 541 (2001);

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 246.30
• Formel: C₁₅H₁₈O₃
• Farbe/Form: White To Off-White
• InChl: InChI=1S/C15H18O3/c1-10(15(17)18)12-7-5-11(6-8-12)9-13-3-2-4-14(13)16/h5-8,10,13H,2-4,9H2,1H3,(H,17,18)
• InChI Key: InChIKey=YMBXTVYHTMGZDW-UHFFFAOYSA-N
• SMILES: CC(C(=O)O)c1ccc(CC2CCCC2=O)cc1