Lubiprostone-d7

CAS: 1217675-13-2

Ref. TR-L473503

Produktinformation

• Name: Lubiprostone-d7
• Synonyme: (11a)-16,16-Difluoro-11-hydroxy-9,15-dioxo-prostan-1-oic Acid-d7, Ru 0211-d7

Beschreibung

Applications Labelled Lubiprostone is a bicyclic fatty acid metabolite analog of Prostaglandin E1. It activates specific chloride channels in the gastrointestinal tract to stimulate intestinal fluid secretion, increase gastrointestinal transit, and improve symptoms of constipation.
References Farthing, M., et al.: Drugs, 56, 11 (1998), Pare, P., et al.: Am. J. Gastroenterol., 96, 3130 (2001), Sloots, C., et al.: Aliment. Pharmacol. Ther., 16, 759 (2002), Coremans, G., et al.: Digestion, 67, 82 (2003),

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 397.51
• Formel: C₂₀H₂₅D₇F₂O₅
• Farbe/Form: Neat
• InChl: InChI=1S/C20H32F2O5/c1-2-3-12-20(21,22)18(25)11-10-15-14(16(23)13-17(15)24)8-6-4-5-7-9-19(26)27/h14-15,17,24H,2-13H2,1H3,(H,26,27)/t14-,15-,17-/m1/s1/i1D3,2D2,3D2
• InChI Key: InChIKey=DBVFKLAGQHYVGQ-QHZIEZROSA-N
• SMILES: [2H]C([2H])([2H])C([2H])([2H])C([2H])([2H])CC(F)(F)C(=O)CC[C@H]1[C@H](O)CC(=O)[C@@H]1CCCCCCC(=O)O