Methyl 4-(4-Fluorophenyl)-6-isopropyl-2-(methylamino)-1,4-dihydropyrimidine-5-carboxylate

CAS: 868755-11-7

Ref. TR-M117750

Produktinformation

• Name: Methyl 4-(4-Fluorophenyl)-6-isopropyl-2-(methylamino)-1,4-dihydropyrimidine-5-carboxylate
• Synonyme: 4-(4-Fluorophenyl)-1,4-dihydro-2-(methylamino)-6-(1-methylethyl)-5-pyrimidinecarboxylic Acid Methyl Ester
• Marke: TRC

Beschreibung

Applications Methyl 4-(4-Fluorophenyl)-6-isopropyl-2-(methylamino)-1,4-dihydropyrimidine-5-carboxylate is a reagent in the synthesis of Methyl 4-(4-Fluorophenyl)-6-isopropyl-2-(methylamino)pyrimidine-5-carboxylate (M303915) which is an intermediate of Rosuvastatin (R700500).
References Laufer, S., et al.: J. Med. Chem., 45, 2733 (2002), Palani, A., et al.: Bioorg. Med. Chem. Lett., 13, 709 (2003),

Chemische Eigenschaften

• Molekulargewicht: 305.347
• Formel: C₁₆H₂₀FN₃O₂
• Farbe/Form: Neat
• InChl: InChI=1S/C16H20FN3O2/c1-9(2)13-12(15(21)22-4)14(20-16(18-3)19-13)10-5-7-11(17)8-6-10/h5-9,14H,1-4H3,(H2,18,19,20)
• InChI Key: InChIKey=WDSBHMAXXRTWJT-UHFFFAOYSA-N
• SMILES: CNC1=NC(c2ccc(F)cc2)C(C(=O)OC)=C(C(C)C)N1